10 Best Laundry Stain Removers in 2022 (Tide, Oxiclean, and More)

OxiClean's bubbling oxygen-based formula helps the power of your regular detergent, breaking down stain-causing proteins and lifting color out of the fabric. Mix it with water to pre-soak, then throw a scoop in with your load of laundry. It's chlorine-free and safe for colorfast material, including carpets and upholstery.

Most negative reviews for OxiClean were due to poor packaging during shipping, although a few people wished the lid fit more tightly. But, overall, the majority of reviewers said it's a must-have, saying it's able to remove sweat, blood, coffee, wine, and more from their clothes. Plus, they noted that it doubles as an effective household cleaner.

From spilled coffee to ketchup drips, accidents happen, and Tide To Go has you covered. Each pen contains a bleach-free formula with a microfiber tip to remove fresh food and drink stains. The pens are mess-free and easy to throw in your bag, luggage, or desk. Tide To Go is not recommended for grease, blood, or ink stains.

A few reviewers warned of an unpleasant smell, while others found the pens dried out too quickly. But most reviewers loved the convenience of this product. They said it's super portable, easy to apply, and saves their clothes from permanent stains while they are out and about. 

To keep your white clothes looking fresh, try the Fels-Naptha Laundry Bar from Purex. It's designed to fight greasy and oily stains, as well as sweat stains and the dreaded ring-around-the-collar. Wet the bar and rub it on the stain as a pre-treatment, or grate the bar into your washing machine and let it work its magic on a whole load.

If you've used this product in the past, note that the formula may have changed. Reviewers warned of a strong new perfume scent. But many were impressed by the stain-lifting power of this bar and said it works on multiple types of stains. They added that it works especially well on sports uniforms!

If your laundry problems include both stains and odors, you will want a product that can fight both. Bac-Out is formulated with a blend of enzyme cultures that break down and absorb organic materials, leaving fabric fresh and clean. It contains no bleach or artificial fragrances or colors and is safe for both children and pets.

Some reviewers said that this doesn't work well on carpets and floors to counteract pet urine. However, on clothing, bedding, and general laundry, many noted that it's super effective. Reviewers said it magically removes stains and odors from heavily soiled cloth diapers, gym clothes, blankets, t-shirts, and more.

For the toughest stains, try Shout's Advanced Action Gel. The concentrated formula features extra surfactants to fight old, set-in stains and comes in an easy-to-use spray bottle. For maximum effectiveness, spray the stain and let it sit overnight. This spray is safe to use on all colorfast machine-washable items. 

While it can be used on a variety of stains, a couple of reviewers noted that it's not as effective on oil and grease. However, many said that it seems to work well on dirt, food, and sweat stains. In addition, most reviewers found that it removed new and old stains from nearly all of their items and said they use it on their clothing regularly.

Zout's Laundry Stain Remover Spray contains three enzymes to fight different types of stains. Protease targets proteins, like the ones found in blood and grass. Amylase targets starchy stains like baby food and barbecue sauce. Finally, lipase fights oil-based stains from things like salad dressing. Use it on cotton or poly-cotton fabric.

As with most stain removers, Zout doesn't work on all stains. Some reviewers had mixed results but most found that it worked on the majority of stains, including older ones. They reported success with greasy stains, food stains, and blood and said it helped save their soiled clothing from being thrown out.

If your stains need a little bit of rubbing to get out, this stick from OxiClean will make your life easier. It features a concentrated gel formula with a nubbed applicator tip, allowing the stain-fighting ingredients to penetrate deep into the fabric. You can pre-treat your item up to seven days before washing.

If you're sensitive to fragrances, steer clear of this product, as reviewers mentioned that it has a strong perfumey scent. Most users loved this gel stick, however, saying it's super convenient and easy to use. In addition, they found it effective against a variety of old and recent stains, including ones from grease, food, and makeup. 

Puracy's spray is made from 99.96 percent naturally-derived ingredients and is biodegradable, vegan, and cruelty-free. The formula contains a blend of six plant enzymes that can tackle all types of stains, including blood, oil, mud, and tomato sauce. It's also free of bleach, sulfates, and dye.

Reviewers weren't huge fans of the nozzle, saying it shoots out a jet rather than a spray. Some also warned that it can stain some fabrics. Still, most reviewers were impressed by how well this natural product works. They said that after letting it sit for a while, it was able to lift dark stains from things like fruit punch, dirt, and chocolate.

Give your favorite detergent some extra oomph with Nature's Miracle Laundry Boost. The bio-enzymatic formula targets severe stains, including urine, feces, and vomit from humans and animals. Squirt it directly on the stain as a pre-treatment, or add it directly to your washing machine.

Reviewers liked the squirt bottle since it allows them to target stains directly. Most users also confirmed that it works well on pet smells and stains, like cat urine. They said it's great for musty towels, workout clothes, and greasy food stains too.

This Grandma's Secret Spot Remover comes in a small bottle that's easy to stash in your car or at work. The environmentally-friendly formula contains no bleach or chlorine and is biodegradable. Use it on all types of stains, including blood, baby food, rust, paint, and turmeric. It's also safe to use on leather!

Some reviewers said it didn't work well on ink and oil stains, but others advised that tough stains may take a bit of elbow grease. On the other hand, many reviewers had excellent results on new and stubborn old stains. They used it for everything from wine to permanent marker.