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Contact Solution for Sensitive EyesHelping You Find the Best
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Contact Solution for Sensitive EyesHelping You Find the Best
  • 10 Best Contact Solutions for Sensitive Eyes of 2025 1
  • 10 Best Contact Solutions for Sensitive Eyes of 2025 2
  • 10 Best Contact Solutions for Sensitive Eyes of 2025 3
  • 10 Best Contact Solutions for Sensitive Eyes of 2025 4
  • 10 Best Contact Solutions for Sensitive Eyes of 2025 5

10 Best Contact Solutions for Sensitive Eyes of 2025

Caring for sensitive eyes requires extra attention, especially regarding contact lens maintenance. Contact solutions designed for sensitive eyes are crucial in ensuring comfort and eye health by minimizing irritation and gently cleaning lenses.

With many options on the market, finding the right contact solution can feel overwhelming. To simplify your search, we’ve spoken with expert optometrist Alex Donovan, OD to highlight the essential factors to consider when choosing contact solutions. Additionally, we’ve curated our ranking of the top 10 contact solutions for sensitive eyes from the bestselling options available on Amazon to help you find one that suits your needs and keeps your eyes refreshed and comfortable.
Last updated 02/14/2025

Quick List - Top Contact Solution for Sensitive Eyes

1

Clear Care

CARE Cleaning & Disinfection Solution
CARE Cleaning & Disinfection Solution

Deep Clean With Gentle Disinfection

2

Opti-Free

Replenish Multi-Purpose Contact Lens Cleaning and Disinfecting Solution
Replenish Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Moisturizing Comfort for Sensitive Eyes

3

Biotrue

Hydration Plus Contact Lens Solution
Hydration Plus Contact Lens Solution

Moisturizing Action for Sensitive Eyes

4

Opti-Free

Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution
Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Long-Lasting Moisture for Sensitive Eyes

5

AO SEPT PLUS

HydraGlade Solution 360ml
HydraGlade Solution 360ml

Deep Clean With Added Moisture Lock

Alex Donovan, OD
Expert
Optometrist
Alex Donovan, OD

Alexander Donovan, O.D. is an optometrist serving the people of Nebraska, USA, passionate about providing the most advanced, quality vision care to its residents and the surrounding areas. Dr. Donovan has extensive experience treating and managing dry eye and other ocular surface diseases. He is particularly invested in uncovering and treating the root cause—not just the symptoms—to provide our dry eye patients with lasting relief. Dr. Donovan’s other areas of expertise include diabetic eye exams, refractive management, the preoperative care of cataracts, glaucoma, SLT, YAG Peripheral Iridotomy, and Capsulotomy, and diagnosing and treating ocular disease.

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Mirai Tanaka
Guide
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Mirai Tanaka

Mirai earned her degree in Marketing Management from De La Salle College of Saint Benilde. Throughout her studies, she gained valuable experience in content planning, research, and editing through various academic projects and internships. Her practicum further strengthened her marketing, sales, and public relations skills, where she learned to craft well-researched and tailored content for different audiences. Mirai applies her expertise to create engaging and informative content on various categories, including fashion, beauty, and lifestyle.

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How Does Contact Lens Solution Differ from Saline Solution?

Expert
Expert

Saline is a simple rinse, while contact lens solution covers a broader range of care, including sanitizing and maintaining lens health.

How Does Contact Lens Solution Differ from Saline Solution?
Not all contact lens solutions are saline; some may not even contain saline. A contact solution is typically multipurpose—used for cleaning, disinfecting, rinsing, and storing contact lenses. On the other hand, saline solution is just a simple, pH-balanced saltwater rinse used to cleanse lenses before they are inserted into your eyes. While saline solution is used to rinse lenses, contact lens solution is a more complex liquid that provides additional functions like cleaning, disinfecting, and maintaining lens health.

How to Choose Contact Solution for Sensitive Eyes

Our guide outlines the key factors to consider when selecting a contact solution for sensitive eyes.
1

Choose a Preservative-Free Contact Solution to Avoid Irritation

Expert
Expert
Some preservatives can trigger allergic reactions, causing redness, itching, or swelling
Choose a Preservative-Free Contact Solution to Avoid Irritation

Avoid preservatives like benzalkonium chloride (BAK), which can harm conjunctival and corneal cells over time, especially with frequent use. BAK, a common preservative in contact lens solutions, effectively prevents contamination but can disrupt ocular tissues, leading to dryness, irritation, and inflammation. A preservative-free formula reduces this risk, providing a gentler alternative for sensitive eyes.


Prolonged exposure can exacerbate discomfort, damage the tear film, and increase the risk of corneal toxicity, particularly for those with sensitive eyes or who wear lenses for extended periods. Choosing preservative-free or contact lens-specific formulas reduces irritation and provides a gentler, safer option for daily use.

2

If You Have Allergies, Choose a Hypoallergenic Option Like Hydrogen Peroxide

Expert
Expert
Hydrogen peroxide solutions are often recommended for people with sensitive eyes or allergies.
If You Have Allergies, Choose a Hypoallergenic Option Like Hydrogen Peroxide

Hydrogen peroxide solutions are hypoallergenic, making them ideal for individuals with allergies. They provide a thorough clean by effectively disinfecting, removing protein deposits, and leaving lenses free of residue, ensuring greater comfort for those with dry or sensitive eyes. Additionally, these solutions are excellent for cleaning and sanitizing contact lenses, as they can kill bacteria, fungi, and other pathogens.


Hydrogen peroxide solutions require neutralization, transforming hydrogen peroxide into harmless water and oxygen. This neutralization typically occurs overnight in a special case or with a neutralizing tablet. Unlike some contact lens solutions, hydrogen peroxide solutions usually require a 4-hour soak time, depending on the product. Since hydrogen peroxide is an oxidizing agent, it can irritate or damage your eyes if used directly on contact lenses. The neutralizing process breaks down hydrogen peroxide into water and oxygen, making the lens solution safe.

Alex Donovan, OD
Optometrist
Alex Donovan, OD
Hydrogen peroxide solutions often require overnight cleaning.
3

For Dry Eyes, Look for Sodium Hyaluronate

Expert
Expert
Sodium hyaluronate can alleviate discomfort, irritation, and dryness, making it especially beneficial for sensitive eyes.
For Dry Eyes, Look for Sodium Hyaluronate

Sodium hyaluronate, a derivative of hyaluronic acid, is renowned for its ability to attract and retain moisture. As a humectant, it binds water to hydrate and lubricate the eye’s surface, ensuring lasting comfort. It also helps maintain the tear film, a protective wet layer on the eye, preventing evaporation or runoff. In contact lens solutions, sodium hyaluronate forms a thin, hydrating layer on the lens surface, reducing dryness and enhancing flexibility and smoothness for improved comfort.


Its soothing properties make it ideal for sensitive-eye wearers prone to irritation, especially in dry or air-conditioned environments or during extended lens wear. Retaining moisture and reducing friction minimizes the risk of discomfort throughout the day. Other beneficial ingredients include Hydraglyde for long-lasting hydration, povidone for reducing friction, borate buffer for pH balance, glycerin for hydration, chondroitin sulfate for lubrication, and taurine to prevent dehydration.

4

Use a Travel-Sized Contact Solution for Convenience on the Go

Expert
Expert
A travel-sized contact solution bottle is a smaller version of a regular contact lens solution bottle that complies with airline liquid regulations.
Use a Travel-Sized Contact Solution for Convenience on the Go
It's not recommended to transfer contact lens solution into another container, as this can compromise its sterility by exposing it to airborne bacteria, dust, or other contaminants. Transferring increases the risk of introducing harmful germs if the equipment or container isn't sterile. Instead, a travel-sized contact solution, typically 30-100 ml and compliant with airline liquid restrictions, is ideal for traveling or on-the-go use.
5

If You Wear RGP Lenses, Use a Rigid Gas Permeable Lens Solution

Expert
Expert
Regular soft lens solutions may not provide the same level of care or may even cause damage to the lenses or discomfort to the wearer.
If You Wear RGP Lenses, Use a Rigid Gas Permeable Lens Solution

RGP contact lenses are custom-made for comfort, offering sharp, stable vision without dehydration or dryness. They require a specific cleaning solution, as soft lens solutions can damage or irritate them. RGP lenses are less absorbent, making them prone to protein buildup, which these specialized solutions effectively remove while protecting the lens structure and eye health.


The wrong solution can cause lens damage, discomfort, and eye health issues like corneal ulcers or dry eye syndrome. For sensitive eyes, daily inspections for damage and weekly checks for protein buildup are recommended, with professional fit evaluations every 6 months to a year.

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10 Best Contact Solution for Sensitive Eyes Ranking

Here are our top picks from the best-selling contact solutions for sensitive eyes, selected based on essential criteria from our buying guide, such as preservative-free formulation, size options, ingredients, and lens compatibility.
Popularity
Filter
Products
Image
Click to purchase
Key features
Details
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution
Travel-Size
Quantity
1

Clear Care

CARE Cleaning & Disinfection Solution

Clear Care CARE Cleaning & Disinfection Solution 1

Deep Clean With Gentle Disinfection

Hydrogen Peroxide

12 fl oz

2

Opti-Free

Replenish Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Opti-Free Replenish Multi-Purpose Contact Lens Cleaning and Disinfecting Solution 1

Moisturizing Comfort for Sensitive Eyes

10 fl oz (Pack of 2)

3

Biotrue

Hydration Plus Contact Lens Solution

Biotrue Hydration Plus Contact Lens Solution 1

Moisturizing Action for Sensitive Eyes

Sodium Hyaluronate

10 fl oz (Pack of 2)

4

Opti-Free

Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Opti-Free Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution 1

Long-Lasting Moisture for Sensitive Eyes

2 fl oz

5

AO SEPT PLUS

HydraGlade Solution 360ml

AO SEPT PLUS HydraGlade Solution 360ml 1

Deep Clean With Added Moisture Lock

Hydrogen Peroxide

12.1 fl oz

6

Boston Simplus

Contact Lens Solution for Gas Permeable Contact Lenses

Boston Simplus Contact Lens Solution for Gas Permeable Contact Lenses 1

Comprehensive Care for Gas Permeable Lenses

3.5 fl oz

7

Biotrue

Multi-Purpose Solution

Biotrue Multi-Purpose Solution 1

Gentle Hydration for Fresh Feeling Lenses

Sodium Hyaluronate

2 fl oz (Pack of 2)

8

Avizor

Ever Clean 225 ml

Avizor Ever Clean 225 ml 1

Gentle Cleaning for Soft and Gas Permeable Lenses

8.5 fl oz

9

Oculus Curae Hyalunix

Multi-Purpose Solution for Contact Lenses

Oculus Curae Hyalunix Multi-Purpose Solution for Contact Lenses 1

Hyaluronic Moisture for Sensitive Eyes

Sodium Hyaluronate

12 fl oz (Pack of 2)

10

Clear Conscience

Cruelty-Free Contact Lens Solution 12oz

Clear Conscience Cruelty-Free Contact Lens Solution 12oz 1

Contact Lens Solution that is Cruelty-Free

12 fl oz (Pack of 3)

If you don't see the product you're looking for, you can request that it be listed.
No.1

Clear Care
CARE Cleaning & Disinfection Solution

CARE Cleaning & Disinfection Solution 1
Source:amazon.com
CARE Cleaning & Disinfection Solution 2
Lowest price
$19.79
Mid
Lowest price
$19.79
Mid
Preservative-Free
Key Ingredients
Hydrogen Peroxide
Rigid Gas Permeable Lens Solution

Deep Clean With Gentle Disinfection

Clear Care Care Cleaning and Disinfection Solution is designed for use with soft and rigid gas-permeable lenses. The solution uses hydrogen peroxide to disinfect lenses, removing debris and proteins. It features a neutralizing disc that converts hydrogen peroxide into water and oxygen, ensuring a gentle cleaning process. This solution is beneficial for users who need a deeper clean and thorough disinfecting process.

Travel-Size
Quantity12 fl oz
Was this Ranking helpful?
No.2

Opti-Free
Replenish Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Lowest price
$15.97
Mid
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution

Moisturizing Comfort for Sensitive Eyes

This multi-purpose solution cleans, disinfects, and stores contact lenses while providing moisture to enhance comfort for those with sensitive eyes. It is designed to replenish and recondition lenses, helping to maintain hydration during wear. The solution contains moisturizing agents that are intended to provide relief from dryness, especially in dry environments. Additionally, it offers standard disinfection properties to ensure lenses are safe to use.

Travel-Size
Quantity10 fl oz (Pack of 2)
No.3

Biotrue
Hydration Plus Contact Lens Solution

Lowest price
$18.99
Mid
Preservative-Free
Key Ingredients
Sodium Hyaluronate
Rigid Gas Permeable Lens Solution

Moisturizing Action for Sensitive Eyes

Biotrue Hydration Plus is a multipurpose solution designed for sensitive eyes. It hydrates and cleans soft contact lenses while providing a comfortable wearing experience. The solution contains a dual-action formula that keeps lenses moist, using a unique blend of ingredients that mimic the natural moisture found in the eyes. It's designed for all-day comfort and helps disinfect and remove buildup on lenses.

Travel-Size
Quantity10 fl oz (Pack of 2)
No.4

Opti-Free
Puremoist Multi-Purpose Contact Lens Cleaning and Disinfecting Solution

Lowest price
$2.94
Low
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution

Long-Lasting Moisture for Sensitive Eyes

Opti-Free Puremoist offers multi-purpose cleaning, disinfecting, and storing contact lenses. The solution is formulated with a moisture-locking agent to help keep lenses hydrated and comfortable for up to 16 hours. It is safe for soft contact lenses and is particularly suited for users who experience discomfort due to dryness.

Travel-Size
Quantity2 fl oz
No.5

AO SEPT PLUS
HydraGlade Solution 360ml

Lowest price
$35.99
High Mid
Preservative-Free
Key Ingredients
Hydrogen Peroxide
Rigid Gas Permeable Lens Solution

Deep Clean With Added Moisture Lock

AO Sept Plus with Hydraglyde is a hydrogen peroxide-based contact lens cleaning and disinfecting solution. It features the Hydraglyde moisture system, which helps lock in moisture and improve lens comfort. This solution is designed for users needing a deep, thorough cleaning and is safe for soft and rigid gas-permeable lenses. The package includes a lens case with a neutralizing disc for safe use.

Travel-Size
Quantity12.1 fl oz
No.6

Boston Simplus
Contact Lens Solution for Gas Permeable Contact Lenses

Lowest price
$10.49
Low Mid
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution

Comprehensive Care for Gas Permeable Lenses

Boston Simplus is a cleaning and conditioning solution for gas-permeable lenses. It features a multi-action formula that cleans, disinfects, and conditions lenses to maintain integrity. The solution helps remove debris and proteins while keeping the lenses moist and comfortable. It's especially recommended for individuals using rigid contact lenses.

Travel-Size
Quantity3.5 fl oz
No.7

Biotrue
Multi-Purpose Solution

Lowest price
$9.92
Low Mid
Preservative-Free
Key Ingredients
Sodium Hyaluronate
Rigid Gas Permeable Lens Solution

Gentle Hydration for Fresh Feeling Lenses

Bio True by Bausch and Lomb is a versatile multi-purpose solution that hydrates and disinfects contact lenses. It mimics the natural chemistry of the eye, offering a gentle yet effective clean. This solution provides long-lasting moisture and is suitable for sensitive eyes, helping to keep lenses feeling fresh all day.

Travel-Size
Quantity2 fl oz (Pack of 2)
No.8

Avizor
Ever Clean 225 ml

Lowest price
$26.55
High Mid
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution

Gentle Cleaning for Soft and Gas Permeable Lenses

Avizor Ever Clean is a cleaning solution for disinfecting and hydrating soft and gas-permeable contact lenses. It removes dirt, proteins, and lipids, offering long-lasting lens protection. This solution is ideal for sensitive eyes, providing a gentle yet effective clean that helps reduce discomfort caused by dry lenses.
Travel-Size
Quantity8.5 fl oz
No.9

Oculus Curae Hyalunix
Multi-Purpose Solution for Contact Lenses

Lowest price
$17.30
Mid
Preservative-Free
Key Ingredients
Sodium Hyaluronate
Rigid Gas Permeable Lens Solution

Hyaluronic Moisture for Sensitive Eyes

Hyalunix Enhanced Moisture Solution hydrates and cleans soft contact lenses. It contains hyaluronic acid, known for its moisture-retaining properties, to ensure comfort throughout the day. The solution is also suitable for disinfection and can store lenses overnight.

Travel-Size
Quantity12 fl oz (Pack of 2)
No.10

Clear Conscience
Cruelty-Free Contact Lens Solution 12oz

Lowest price
$42.99
High
Preservative-Free
Key Ingredients
Rigid Gas Permeable Lens Solution

Contact Lens Solution that is Cruelty-Free

Clear Conscience Contact Lens Solution offers a gentle yet effective cleaning solution for contact lenses. This cruelty-free formula is free from harsh chemicals, ensuring a safe and comfortable experience for users with delicate eyes. The 12oz bottle provides enough solution for extended use, keeping your lenses clean, disinfected, and moisturized. Ideal for those who prioritize ethical, animal-free products, this solution is perfect for daily care, providing clear vision without the irritation that other solutions may cause.

Travel-Size
Quantity12 fl oz (Pack of 3)
The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

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