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  • 10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More) 1
  • 10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More) 2
  • 10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More) 3
  • 10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More) 4
  • 10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More) 5

10 Best Ergonomic Mouse in 2022 (Logitech, Razer, and More)

If you work in an office or play computer games, your wrist may hurt after a while. This happens since the standard mouse doesn't encourage your hands to sit in a comfortable position, so you end up facing aches and pains. However, ergonomic mice offer more comfort while you spend hours at the computer, so we created a list of our 10 favorite ergonomic mice.


We put Logitech's wireless mouse at the top of the list since it works on Windows, Mac, and Linux computers, it has a three-year battery life, and it offers an ergonomic design. Make sure to go through the list and check the buying guide, so you can find an ergonomic mouse for your needs.

Last updated 09/26/2023

Quick List - Top Ergonomic Mouse

1

Anker

CE100

Best for Simple Office Use

2

Logitech

MX Ergo Wireless Trackball Mouse‎910-005177
MX Ergo Wireless Trackball Mouse

Best for Minimal Hand Movement

3

Logitech G

‎910-004360

Best for Gamers and People Who Want Multiple Buttons

4

Censi

Best for People Who Forget to Turn Off The Mouse

5

iClever

E03-1877N-01

Best for People Who Need a Quiet Mouse

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Table of Contents

How to Choose Ergonomic Mouse

An ergonomic mouse allows you to get things done more efficiently on the computer and alleviate the pain that using a mouse can lead to. Reflect on what you don't like about your current mouse, what you would like to be able to do with an ergonomic mouse, and how your space is set up. 

1

Get a Style Based on Use, Like Gaming or Work

Get a Style Based on Use, Like Gaming or Work

A casual computer user's needs will be different from serious gamers or people who rely on computers for their jobs. You may want to focus more on comfort with casual use, so a standard or trackball shape works best. On the other hand, office workers may prefer a vertical mouse since it doesn't hurt the wrist as much as the other options.


The shape of the mouse influences how comfortable the mouse is to use and its level of accuracy and precision. For example, a vertical mouse works better for casual or work use since it reduces pain. On the other hand, a gamer may want a standard mouse with additional features since they need to press multiple buttons and make fast movements.


You also need to consider which operating system (OS) you use. For example, if you plan to only use Windows, Mac, or Linux, you can get one type with your supported OS. If you want to use your mouse for multiple computers, you may want to get a mouse with multiple OS support.

2

Decide Which Mouse Shape Is Best for You

Think about how you would like to use your ergonomic mouse and try to imagine what shape will position your hand, arm, and wrist in a way that reduces pain.

Vertical Mice Keep Your Hand in a Natural Position

Vertical Mice Keep Your Hand in a Natural Position

Vertical ergonomic mice keep your hand in a natural handshake position, which is anatomically better for long-term computer use. Many people feel short- and long-term relief in carpal tunnel syndrome symptoms or repetitive stress injuries (RSI).


However, they can be awkward or difficult to get used to at first. Another downside of the vertical ergonomic mouse is that it may compromise precision and accuracy, so gamers or those who need precise and accurate movements may run into some difficulty. 

Trackball Mice Prevent Arm Strain

Trackball Mice Prevent Arm Strain

Those who are experiencing shoulder or arm pain due to computer mice may want to consider an ergonomic trackball mouse. The trackball controls the movement of the mouse, meaning you only use your fingers to maneuver the mouse, eliminating the wrist and arm movements of using a mouse. 

Adjusted Traditional Models for Familiarity

Adjusted Traditional Models for Familiarity

Some people want to use traditional mice with some comfortable features to make them more ergonomic. For example, some mice have additional space for the thumb, ring, and pinky fingers to rest on them. They may include rubber or soft material along the fingers to make them more comfortable.


This type works best for people who don't want to adjust to another mouse style. That way, they can immediately use the mouse without awkwardly transitioning to it.

Left- or Right-Handed Options Provide Better Relief

Left- or Right-Handed Options Provide Better Relief

Some people may want to choose a mouse based on the hand they prefer. For example, many computer mice have a right-handed design, so they have a thumb indent on the left side to comfortably rest the thumb. However, some mice use a left-handed design with the thumb rest on the left side.


You may come across computer mice with an ambidextrous design. This means neither side includes any finger rests, but they can be used by anyone. An ambidextrous design works best if you need to share your computer or want to give your dominant hand a break sometimes.

3

Choose a Connection Option Based on Reliability and Lag

Like most computer mice, an ergonomic mouse primarily connects to your computer by Bluetooth, wireless connection, or wired connection.

Bluetooth Connections Don't Require Any Extra Tools

Bluetooth Connections Don't Require Any Extra Tools

A Bluetooth connection is an easy, USB- and wire-free way to connect a mouse and a computer. This is a good option for those who don't have an open USB port on their computer, because you can connect through the Bluetooth function on your computer. 


However, those who aren't that great with technology may find it difficult to figure out how to connect the mouse. And as with all wireless things, there is always a risk of disconnecting or lags in your mouse. Bluetooth mice are convenient and compact but require battery charging or changing.

Wireless Connections Are Easy

Wireless Connections Are Easy

Wireless connections typically use 2.4GHz technology to connect a small USB dock. This is an easier wireless connection that doesn't require any extra steps other than putting the USB in your computer and turning the mouse on to make the setup easy.


Some mice are designed with a little port in the mouse to store away the USB dock, but there are many that don't have that design. If you are the type of person who loses things easily, looking for a mouse with a storage port or choosing a mouse that connects differently may be a good idea.


Wireless devices need a power source. For example, the mouse may require you to place AA batteries in it to work. Others may let you recharge the batteries. Replaceable batteries can run out, but rechargeable ones may be more difficult to replace if they stop holding a charge.

Wired Mice Are the Most Reliable

Wired Mice Are the Most Reliable

Wired connections are the most reliable. Because the mouse is directly connected to the computer, you don't have to worry about the battery running out or the mouse disconnecting from the computer. Most wired mice also tend to be faster than their wireless counterparts.


However, the wire can be restricting or just plain annoying, possibly contributing to a feeling of clutter. Wired mice tend to be bothersome and space-consuming to travel with as well.

4

Consider the Number of Buttons and DPI

Consider the Number of Buttons and DPI

The number of buttons is another component think about when shopping for a mouse. More buttons allow you to perform more actions without using your keyboard. Mice with additional buttons often include them along the side of the mouse, so you can press them with your thumb.


On the technical side, features such as DPI settings allow you to control how quickly and precisely the mouse moves. A high DPI is beneficial for those who play FPS games, those who need to tweak fine levels of details, or those with a high-resolution monitor. 

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10 Best Ergonomic Mouse Ranking

Here are the best Ergonomic Mouse, ranked according to 10 Best Ergonomic Mouse (as of 11-04-2022). The products are ranked independently by mybest.
Popularity
Products
Image
Click to purchase
Key features
1

Anker

CE100

Anker  1

Best for Simple Office Use

2

Logitech

MX Ergo Wireless Trackball Mouse‎910-005177

Logitech MX Ergo Wireless Trackball Mouse 1

Best for Minimal Hand Movement

3

Logitech G

‎910-004360

Logitech G  1

Best for Gamers and People Who Want Multiple Buttons

4

Censi

Censi  1

Best for People Who Forget to Turn Off The Mouse

5

iClever

E03-1877N-01

iClever  1

Best for People Who Need a Quiet Mouse

6

Kensington

K72337US

Kensington  1

Best for an Accessible Trackball

7

DeLUX

M618Plus RGB

DeLUX  1

Best Vertical Mouse for Large Hands

8

Perixx

Perixx  1

Best Vertical Mouse for Left-Handed Users

9

Microsoft

78010664

Microsoft  1

Best for Taking to Class or on Business Trips

10

Microsoft

L6V-00001

Microsoft  1

Best for Easy Scrolling

If you don't see the product you're looking for, you can request that it be listed.
No.1

Anker
CE100

 1
Source:amazon.com
 2
Source:amazon.com
Reference price
$32.99
Mid
Reference price
$32.99
Mid

Best for Simple Office Use

Pros:

  • Includes a DPI button
  • A vertical tilt to make it more ergonomic
  • Offers five buttons to make browsing easier
  • Nearly five-foot cable

Cons:

  • Some people report inconsistent performance from the scroll wheel
  • Some buttons won't function on Macs

This mouse includes a vertical tilt on it to add additional comfort while using the mouse for long periods of time. It also supports the three common operating systems, so it can work on whatever computer your office decides to use.


A couple of reviewers found the scroll wheel hard to press and said it didn't always respond to scrolling. However, multiple reviewers found the mouse comfortable to use. They also liked how it included an additional button to control the DPI.

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No.2

Logitech
MX Ergo Wireless Trackball Mouse‎910-005177

Reference price
$86.10
High

Best for Minimal Hand Movement

Pros:

  • Has eight buttons
  • Over 1500 DPI range
  • Includes rechargeable batteries
  • Usable on the three most common operating systems
  • A trackball on the left side to give the thumb easy access

Cons:

  • Some people found the mouse too small
  • The trackball can get in the way if you don't want to use it

This mouse puts an emphasis on the trackball, so make sure you want to use it if you plan to buy it. It also lets you use it wirelessly while allowing you to recharge the batteries as needed.


A few reviewers felt the mouse and trackball were too small for their hands. Nevertheless, various reviewers appreciated how the mouse was wireless and incorporated Bluetooth. They also loved how they could charge the batteries and use the mouse at the same time.

No.3

Logitech G
‎910-004360

Reference price
$21.99
Low Mid

Best for Gamers and People Who Want Multiple Buttons

Pros:

  • Multiple programmable buttons
  • Ambidextrous design
  • Plenty of DPI settings
  • Designed for gaming and quick movements
  • Includes rubber indents for the thumb to comfortably grip

Cons:

  • Doesn't work on Linux systems
  • Lacks durability, according to reviewers

This gaming mouse uses an ambidextrous design, and this along with the rubber grips makes it comfortable to hold. It also includes tons of DPI settings to adjust the speed of the mouse and meet the needs of the gamer.


A couple of reviewers said the mouse wasn't durable, so after a few months, it would break. On the bright side, a fair portion of reviewers pointed out how left-handed people could comfortably use this mouse. They also felt it was a great mouse to use while playing games.

No.4

Censi

Reference price
$19.99
Low Mid

Best for People Who Forget to Turn Off The Mouse

Pros:

  • Works on the three common OS types
  • Includes multiple buttons
  • Available in left- and right-handed variations
  • Offers three DPI levels
  • Sits at a 33-degree angle
  • Includes resting spots for the thumb and fingers

Cons:

  • Doesn't offer a rechargeable battery
  • A smaller size some people may not like

This mouse is available in left- and right-handed options, as well as different sizes. It also includes resting spots for your fingers, so you can focus on comfort while using the mouse. 


A couple of reviewers didn't like how the mouse felt too small and condensed for their hands. However, multiple reviewers loved how the mouse included a battery-saving mode. They also loved how they could keep using the mouse without hurting their hands.

No.5

iClever
E03-1877N-01

Reference price
$19.99
Low Mid

Best for People Who Need a Quiet Mouse

Pros:

  • 10-minute power-off feature
  • Can choose between four DPI modes
  • Has quiet buttons
  • Sits at a 45-degree angle to offer more comfort
  • Includes a 49-foot wireless range

Cons:

  • Requires AA batteries to function

This mouse has quiet buttons, so you don't need to worry about your clicking causing a distraction. It also offers a 49-foot range, so you can sit far from the USB port and still use your mouse.


A couple of reviewers felt the mouse didn't last as long as they wanted since the mouse sometimes broke down after a few weeks. Nevertheless, quite a few reviewers felt the mouse sat at a good vertical angle for them. They also appreciated how the buttons were quiet.

No.6

Kensington
K72337US

Reference price
$37.96
High Mid

Best for an Accessible Trackball

Pros:

  • Available in a wired and wireless variation
  • Offers an ambidextrous design
  • Includes an easy-to-access trackball
  • A large base designed for any hand size
  • Includes a scroll wheel around the trackball

Cons:

  • Only includes two buttons
  • Not compatible with Linux computers

This mouse has a large trackball in the middle of it to make it easy for anyone to use it. It also comes in a wired and wireless version, so you can choose your ideal connection type.


A couple of reviewers felt the buttons were too out of the way to easily reach while using the trackball. Despite that point, loads of reviewers found the trackball easy to move and use. They also appreciated how it had an ambidextrous design to make it more accessible.

Best Vertical Mouse for Large Hands

Pros:

  • Offers over 3000 DPI range
  • Lets you program all the mouse buttons
  • Has protruding buttons to make them easier to find
  • Offers six buttons
  • Includes RGB color chasing lights that can also be turned off

Cons:

  • Not compatible with Linux systems
  • Not as fast horizontal movement

This mouse lets you adjust it in multiple ways such as changing the DPI, programming the buttons, and adjusting the lights. You also have protruding buttons to make it easier to find the buttons when you need them. This DeLUX model is designed for large hands specifically.


A couple of reviewers found the horizontal movement on this mouse slow and sluggish. On the other hand, multiple reviewers stopped facing pain and numbness in their hands while using this mouse. They also found the buttons easy to find whenever they use the mouse.

Best Vertical Mouse for Left-Handed Users

Pros:

  • Includes wired and wireless versions
  • Ergonomic shape designed for left-handed users
  • Multiple buttons designed for office use
  • Rubber-coated surface to prevent the hand from slipping
  • Offers an area to rest the thumb

Cons:

  • Only includes two DPI settings
  • Doesn't support Linux

This mouse offers an ergonomic design for left-handed users, so you can comfortably navigate your computer tasks. It has multiple buttons to help you go back to previous pages, move forward, and perform other necessary actions.


A small portion of reviewers said the mouse wheel broke, or felt the buttons were hard to depress. Despite that, most reviewers appreciated the ergonomic design and found it comfortable. They also loved how they could use the mouse and not face problems with their wrist.

Best for Taking to Class or on Business Trips

Pros:

  • It offers an ambidextrous design
  • You can adjust the arc of the mouse
  • Easy to flatten and store the mouse or travel with it
  • Includes a touch-to-scroll feature for easy navigation

Cons:

  • It doesn't provide Linux support
  • Requires batteries to work
  • It doesn't offer DPI settings on the mouse itself

This mouse lets you adjust the shape to flatten it out or offer more of a curve based on your needs. It also has an ambidextrous design, so it works great for left- and right-handed people.


A few reviewers ran into problems with the scroll function breaking on them after a few months of use. Despite that point, multiple reviewers loved the smooth and ergonomic design. They also appreciated its portable and small size, so they can take it with them as needed.

No.10

Microsoft
L6V-00001

Reference price
$40.50
High Mid

Best for Easy Scrolling

Pros:

  • The mouse's curve naturally matches a hand's curve
  • Includes a Windows button for easy access to the menu
  • It offers an area for the thumb to comfortably rest
  • Uses four-way scrolling to scroll up, down, left, or right while navigating webpages
  • Reduces pressure on carpal tunnel areas

Cons:

  • You can't adjust the DPI settings on the mouse itself
  • Full support only on Windows OS
  • Requires batteries to function
  • Reviewers report poor durability

This mouse is wireless, so you just need to plug in the USB dongle to use it on your computer. It includes four-way scrolling, which makes it stand out from similar options. It's designed for Windows, with a start menu button placed for easy access.


The main complaints from reviewers were about it breaking, and difficulty getting the warranty honored. However, even those who faced these issues this loved the design so much they purchased another! They agree it's really comfortable, and say you can use it with a Mac, except for the Windows home button.

Amazon's Best Selling Computer Mice

Top 5 Ergonomic Mouse

No. 1: AnkerCE100

No. 2: LogitechMX Ergo Wireless Trackball Mouse‎910-005177

No. 3: Logitech G ‎910-004360

No. 4: Censi

No. 5: iCleverE03-1877N-01

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The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

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