mybest
Vitamin B12 SupplementsHelping You Find the Best
mybest
Vitamin B12 SupplementsHelping You Find the Best
  • 10 Best Vitamin B12 Supplements  [Registered Dietitian-Reviewed Buying Guide] 1
  • 10 Best Vitamin B12 Supplements  [Registered Dietitian-Reviewed Buying Guide] 2
  • 10 Best Vitamin B12 Supplements  [Registered Dietitian-Reviewed Buying Guide] 3
  • 10 Best Vitamin B12 Supplements  [Registered Dietitian-Reviewed Buying Guide] 4
  • 10 Best Vitamin B12 Supplements  [Registered Dietitian-Reviewed Buying Guide] 5

10 Best Vitamin B12 Supplements [Registered Dietitian-Reviewed Buying Guide]

Choosing the right Vitamin B12 supplement can be overwhelming, given the plethora of options available. With various brands, ingredient formulations, and dosage forms, it's crucial to select one that suits your dietary needs and health goals.


To simplify the process, we've partnered with Registered Dietitian Nutritionist, Kathy Shattler. Together, we’ll walk you through the key factors to consider when choosing a supplement and highlight some top-rated Vitamin B12 options. Our detailed guide covers everything from the essential health benefits of B12 to the importance of absorption rates, ensuring you find the perfect supplement for your lifestyle and nutritional needs.


Read on to find the best Vitamin B12 supplements and make an informed choice for your health.

Last updated 07/03/2024

Quick List - Top Vitamin B12 Supplement

1

Garden of Life, Inc.

Vitamin CodeRaw B-12
Raw B-12

Clean and Natural B12 for Vegans

2

Nature Made Nutritional Products

Nature MadeVitamin B12 Extra Strength
Vitamin B12 Extra Strength

60-Day Supply from a Trusted Pharmacist-Recommended Brand

3

Jarrow Formulas

Jarrow FormulasMethyl B-12 & Methyl Folate Lemon
Methyl B-12 & Methyl Folate Lemon

Lemon-Flavored B-12 with Non-GMO Ingredients

4

Naturelo Premium Supplements LLC

Naturelo Vegan Vitamin B12 Supplement With Spirulina
Vegan Vitamin B12 Supplement With Spirulina

Vegan B12 with Organic Spirulina

5

Amazon.com Services LLC

Amazon BasicsVitamin B12 3000 mcg Gummies
Vitamin B12 3000 mcg Gummies

High-Dose B12 Raspberry-Flavored Vegan Gummies

Kathy Shattler, MS, RDN
Expert
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

A Registered Dietitian Nutritionist for over 25 years, Kathy has mastered numerous medical specialties and teaching methods: health promotion, counseling, academic teaching, endocrinology, psychiatry/mental health, supplements, diabetes, obesity, heart disease, aging, and alternative medicine. Experiences include: -Managing her own telehealth/nutrition consulting business -Directing a continuing education program for RDs and nurses -Consulting for long-term care regulatory affairs -Working with State and local health departments -Coordinating diabetes education programs Her experiences led her to reach people with life-changing information as a medical editor and writer. For over five years, Kathy has acquired increasingly complex roles. Passionate about the root causes of disease, she obtained her certification in Integrative Medicine and Functional Nutrition from the Academy of Nutrition and Dietetics three years ago. This series continues to influence her approach to writing.

Kathy Shattler, MS, RDN's Profile
…Continue reading
mybest US Editors
Guide
Editing Dept.
mybest US Editors

mybest US' editing team consists of experienced members who have backgrounds in writing, editing, translation, and more. We are dedicated to researching what makes a product or service the best to users in the US in order to create top-quality articles. From skincare, to kitchen appliances, and to DIY supplies, our mission is to find the best ones for you.

mybest US Editors's Profile
…Continue reading
The expert oversees the Buying Guide only, and does not determine the products and services featured.

Table of Contents

How Much Vitamin B12 Do You Need?

Expert
Expert

How much B12 you need depends on the condition being treated, and it is best to consult your doctor or RDN to determine the dose.

How Much Vitamin B12 Do You Need?

On average, adults need a recommended daily allowance of 2.4 micrograms of Vitamin B12, primarily obtained through diet from animal products like meat, dairy, and eggs. Vegans, older adults, and those with absorption issues due to conditions like Crohn's disease or medications such as antacids and metformin may require supplements to meet their needs. The proper amount for each need can vary by individual. Always consult with a doctor or registered medical professional before starting any supplements.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
Breastfeeding and lactating women should not take higher than the RDI, which is 2.6 and 2.8 mcg, respectively. People with pernicious anemia need 500-1,000 mcg per day, and those with Alzheimer's disease have responded to 50 mcg per day. 

In conditions where absorption is low, like atrophic gastritis, you have to take higher amounts than the RDI; this is called medical nutrition therapy and is only licensed to be practiced by RDs. I recommend an individualized assessment for supplement prescriptions.

How to Choose a Vitamin B12 Supplement

Here are the points to keep in mind when choosing the best Vitamin B12 supplement for you.
1

For High-Quality B12 Supplements, Opt For Third-Party Tested Products

Expert
Expert

Choose supplements that are third-party tested to guarantee potency and quality. In addition, read labels for harmful substances like maltodextrin or silicon dioxide.

For High-Quality B12 Supplements, Opt For Third-Party Tested Products

For those prioritizing high-quality B12 supplements, it's essential to opt for products that undergo third-party testing to ensure purity and accuracy. You can look for trusted certifications such as the USP Verified Mark and NSF Certification


Supplements like Nature Made's B12 Softgels are recommended for their quality and adherence to strict verification standards that validate supplement label accuracy. Avoiding additives such as silicon dioxide and maltodextrin, which can adversely affect gut health, is crucial when selecting supplements to support overall well-being and health maintenance.

2

Choose a Form Based on Your Lifestyle Needs

B12 comes in many different forms. Some may be more suitable for certain users than others. Remember to consider your preferences and needs.

Tablets, Capsules, Lozenges, Gummies For High Dosage And Convenience

Expert
Expert

Pills and lozenges offer higher B12 doses and fewer additives, providing convenient options for effective supplementation.

Tablets, Capsules, Lozenges, Gummies For High Dosage And Convenience

When considering B12 supplements for convenience, tablets, capsules, and lozenges are preferred for their higher doses and fewer additives. While gummies tend to contain additives, they can be a good option for individuals who find pills difficult to swallow. These forms ensure effective daily supplementation, with lozenges offering sublingual absorption benefits

Nasal Sprays, Gels, Liquid Drops For Fast Absorption And Dosage Adjustment

Expert
Expert

Liquid forms may offer faster absorption and are beneficial for individuals with swallowing difficulties or those requiring precise dosage adjustments.

Nasal Sprays, Gels, Liquid Drops For Fast Absorption And Dosage Adjustment

Nasal sprays, gels, and liquid drops of vitamin B12 are favored for their quicker rate of absorption, bypassing digestive issues, and offering convenience. While they provide quick results, their overall absorption efficiency compared to traditional forms remains similar, necessitating consultation with healthcare providers for optimal dosage and effectiveness.


What about transdermal patches? We asked Registered Dietitian Nutritionist, Kathy Shattler whether they are a good choice for vitamin B12 supplementation below.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

B12 transdermal patches lack researched effectiveness and are considered health fraud due to their unapproved status and inability to make structure-function claims approved by the FDA. The absorption rate through the skin barrier is minimal, around 1%, which is not sufficient for therapeutic use, primarily due to the particle size barrier.

3

For Those With Plant-Based Diets, Check for Vegan-Certified Supplements

Expert
Expert
People with a vegan diet should choose B12 supplements carefully, opting for vegan-certified capsules made of cellulose to avoid animal-derived gelatin found in some products.
For Those With Plant-Based Diets, Check for Vegan-Certified Supplements
Since B12 supplements can be important for a plant-based diet, checking whether a product actually aligns with your needs can seem tricky. Vegan B12 supplements are typically free from animal-derived ingredients like gelatin, which can be found in non-vegan capsules. It's recommended to opt for products certified by organizations like the Vegan Society with the Vegan Trademark to guarantee they meet vegan standards. 
Was the Buying Guide helpful?

10 Best Vitamin B12 Supplements Ranking

Here are the best Vitamin B12 supplements we found online from sites like Amazon and iHerb. mybest independently ranked the products according to our expert-backed buying guide.
Popularity
Filter
Products
Image
Click to purchase
Key features
Details
Vitamin B12 Content
Organic
Product Amount
Type of B12
Vegan
Form
1

Garden of Life, Inc.

Vitamin CodeRaw B-12

Garden of Life, Inc. Raw B-12 1

Clean and Natural B12 for Vegans

1000mcg

30 capsules

Methylcobalamin

Capsules

2

Nature Made Nutritional Products

Nature MadeVitamin B12 Extra Strength

Nature Made Nutritional Products Vitamin B12 Extra Strength 1

60-Day Supply from a Trusted Pharmacist-Recommended Brand

2500mcg

60 tablets

Cyanocobalamin

Tablets

3

Jarrow Formulas

Jarrow FormulasMethyl B-12 & Methyl Folate Lemon

Jarrow Formulas Methyl B-12 & Methyl Folate Lemon 1

Lemon-Flavored B-12 with Non-GMO Ingredients

1000mcg

100 tablets

Methylcobalamin

Tablets

4

Naturelo Premium Supplements LLC

Naturelo Vegan Vitamin B12 Supplement With Spirulina

Naturelo Premium Supplements LLC Vegan Vitamin B12 Supplement With Spirulina 1

Vegan B12 with Organic Spirulina

1000mcg

90 capsules

Methylcobalamin

Capsules

5

Amazon.com Services LLC

Amazon BasicsVitamin B12 3000 mcg Gummies

Amazon.com Services LLC Vitamin B12 3000 mcg Gummies 1

High-Dose B12 Raspberry-Flavored Vegan Gummies

3000mcg

100 gummies

Methylcobalamin, Hydroxycobalamin

Gummies

6

Cymbiotika

CymbiotikaLiposomal Vitamin B12 + B6

Cymbiotika Liposomal Vitamin B12 + B6 1

Vegan Liquid Supplement for Enhanced Absorption

1250mcg

2.0 fl. oz.

Methylcobalamin, Adenosylcobalamin, Hydroxycobalamin

Spray

7

Nutrawise

YoutheoryB12B6 Capsule

Nutrawise B12B6 Capsule 1

Vegan B12B6 Capsules for Immune and Nerve Health

1000mcg

60 capsules

Methylcobalamin

Capsules

8

Bronson Pharmaceuticals

BronsonVitamin B12 Sustained Release Non-GMO

Bronson Pharmaceuticals Vitamin B12 Sustained Release Non-GMO 1

Sustained Release for Steady B12 Levels

1000mcg

100 tablets

Cyanocobalamin

Tablets

9

Nature's Bounty, Inc.

Nature's BountyVitamin B-12

Nature's Bounty, Inc. Vitamin B-12 1

Quick-Dissolve B12 for Easy Absorption

2500mcg

300 tablets

Methylcobalamin

Tablets

10

Doctor's Best, Inc.

Doctor's BestFully Active B12

Doctor's Best, Inc. Fully Active B12 1

Gluten-Free, Non-GMO B12 for Overall Well-Being

1500mcg

180 capsules

Methylcobalamin

Capsules

If you don't see the product you're looking for, you can request that it be listed.
No.1

Garden of Life, Inc.
Vitamin CodeRaw B-12

Raw B-12 1
Source:amazon.com
Raw B-12 2
Source:amazon.com
Lowest price
$13.29
Lowest price
$13.29
Vitamin B12 Content1000mcg
Type of B12Methylcobalamin
Vegan

Clean and Natural B12 for Vegans

Garden of Life B12 - Vitamin Code Raw is an essential supplement designed to support overall health, particularly for vegetarians and vegans. Vitamin B12 is crucial for protecting against anemia, maintaining healthy nerve and red blood cells, and aiding in DNA synthesis. This raw, food-created vitamin B12 claims to offer metabolism support, mental and physical energy, central nervous system health, and digestive support. 


Additionally, it includes a blend of probiotics and enzymes for digestive health and a vegetable blend for extra nutritional support. This vegan B12 vitamin is raw, gluten-free, and dairy-free, with no binders or fillers, making it a clean and natural choice for those seeking to maintain their B12 levels.

Organic
Product Amount30 capsules
FormCapsules
Was this Ranking helpful?
No.2

Nature Made Nutritional Products
Nature MadeVitamin B12 Extra Strength

Vitamin B12 Extra Strength 1
Source:amazon.com
Vitamin B12 Extra Strength 2
Source:amazon.com
Vitamin B12 Extra Strength 3
Source:amazon.com
Lowest price
$11.18
Low Mid
Lowest price
$11.18
Low Mid
Vitamin B12 Content2500mcg
Type of B12Cyanocobalamin
Vegan

60-Day Supply from a Trusted Pharmacist-Recommended Brand

Nature Mads's tablets are designed to help break down food into energy your body can use all day long. Sourced from high-quality ingredients, this gluten-free supplement contains no added colors or artificial flavors. 


Each bottle provides a 60-day supply, with adults recommended to take one tablet daily with water and a meal. Trusted for its quality, Nature Made is the #1 Pharmacist Recommended Vitamin and Supplement Brand, and their supplements are verified by the United States Pharmacopeia (USP) for ingredients, potency, and manufacturing process.

Organic
Product Amount60 tablets
FormTablets
No.3

Jarrow Formulas
Jarrow FormulasMethyl B-12 & Methyl Folate Lemon

Lowest price
$15.29
Vitamin B12 Content1000mcg
Type of B12Methylcobalamin
Vegan

Lemon-Flavored B-12 with Non-GMO Ingredients

Jarrow Formulas' Extra Strength Methyl B-12 comes in chewable tablets that support energy metabolism, brain and nerve health, and cardiovascular function. Each bottle contains 100 lemon-flavored chewable tablets, providing a 100-day supply. 


This vegan, gluten-free supplement features active forms of Vitamins B12, B9, and B6, which are essential for cell function and cardiovascular health. It is made with non-GMO ingredients and is free from common allergens.

Organic
Product Amount100 tablets
FormTablets
No.4

Naturelo Premium Supplements LLC
Naturelo Vegan Vitamin B12 Supplement With Spirulina

Lowest price
$17.96
Vitamin B12 Content1000mcg
Type of B12Methylcobalamin
Vegan

Vegan B12 with Organic Spirulina

NATURELO Vegan B12 offers a potent 1000 mcg dose of methylcobalamin, a bioactive form of vitamin B12. It is ideal for vegans and vegetarians who may miss out on B12 from plant-based foods. 


This supplement includes organic spirulina, which provides natural B vitamins, protein, and essential minerals. It is made from non-GMO, gluten-free, soy-free, vegan, and vegetarian ingredients and contains no coloring, flavoring, or preservatives.

Organic
Product Amount90 capsules
FormCapsules
No.5

Amazon.com Services LLC
Amazon BasicsVitamin B12 3000 mcg Gummies

Lowest price
$19.79
High Mid
Vitamin B12 Content3000mcg
Type of B12Methylcobalamin, Hydroxycobalamin
Vegan

High-Dose B12 Raspberry-Flavored Vegan Gummies

Amazon Basics' Vitamin B12 3000 mcg gummies claim to support energy production, red blood cell formation, brain function, cognition, and immune health. 


These soft, pectin-based vegan gummies, which come in a raspberry flavor, are free from gluten, wheat, dairy, soy, and egg. Each pack contains 200 gummies, which, when taken as directed, provide over a three-month supply.

Organic
Product Amount100 gummies
FormGummies
No.6

Cymbiotika
CymbiotikaLiposomal Vitamin B12 + B6

Lowest price
$48.00
High
Vitamin B12 Content1250mcg
Type of B12Methylcobalamin, Adenosylcobalamin, Hydroxycobalamin
Vegan

Vegan Liquid Supplement for Enhanced Absorption

Cymbiotika Liposomal Vitamin B12 Liquid Supplement features a blend of the three most bioactive forms of vitamin B12 (methylcobalamin, hydroxocobalamin, and adenosylcobalamin) along with vitamin B6. This B vitamin complex supports energy production, mood, heart health, and the health of skin, hair, and nails. Utilizing advanced liposomal technology, this formula ensures enhanced absorption and bioavailability. T


The supplement includes l-methylfolate to aid in red blood cell formation and neurotransmitter production. Cymbiotika’s supplement is gluten-free, soy-free, keto, vegan, and free from chemicals, animal products, alcohols, additives, and preservatives.

Organic
Product Amount2.0 fl. oz.
FormSpray
No.7

Nutrawise
YoutheoryB12B6 Capsule

Lowest price
$9.59
Low Mid
Vitamin B12 Content1000mcg
Type of B12Methylcobalamin
Vegan

Vegan B12B6 Capsules for Immune and Nerve Health

Youtheory's B12B6 Capsule combines essential nutrients to support brain health, a healthy immune system, and overall well-being. This supplement may aid in the metabolism of DNA, proteins, carbohydrates, and fats, converting food into cellular energy. 


Vitamins B12 and B6 promote healthy nerve and blood cells, which help remove harmful toxins from the body. These daily vitamins are designed for men and women to enhance brain health and energy levels, supporting your wellness journey at any life stage. The capsules are vegan, dairy-free, soy-free, and contain no gluten ingredients.

Organic
Product Amount60 capsules
FormCapsules
No.8

Bronson Pharmaceuticals
BronsonVitamin B12 Sustained Release Non-GMO

Lowest price
$7.99
Low
Vitamin B12 Content1000mcg
Type of B12Cyanocobalamin
Vegan

Sustained Release for Steady B12 Levels

Bronson Vitamin B12 Sustained Release provides 1000 mcg of cyanocobalamin in a superior sustained release tablet. This formulation releases slowly over time to maintain steady B12 levels, supporting healthy energy levels throughout the day and aiding in the function of the nervous system and brain cells. 


The vegan formula is non-GMO, gluten-free, and soy-free, ensuring purity and quality. Bronson claims to adhere to rigorous standards for purity, potency, and integrity.

Organic
Product Amount100 tablets
FormTablets
No.9

Nature's Bounty, Inc.
Nature's BountyVitamin B-12

Lowest price
$35.99
High Mid
Vitamin B12 Content2500mcg
Type of B12Methylcobalamin
Vegan

Quick-Dissolve B12 for Easy Absorption

Nature’s Bounty's Vitamin B-12 Quick Dissolve Tablets offer 1000 mcg of methylcobalamin, the active form of Vitamin B12, per serving. They dissolve quickly with a natural cherry flavor, making them a convenient option for those who prefer not to swallow pills. 


The vegetarian-friendly tablets are free from sugar, artificial flavors, soy, gluten, fish, and dairy. Third-party tested for quality and efficacy, these sublingual tablets are placed under the tongue for 30 seconds before swallowing, ensuring effective absorption. This is especially beneficial for individuals with digestive or malabsorption issues.

Organic
Product Amount300 tablets
FormTablets
No.10

Doctor's Best, Inc.
Doctor's BestFully Active B12

Lowest price
$12.99
Vitamin B12 Content1500mcg
Type of B12Methylcobalamin
Vegan

Gluten-Free, Non-GMO B12 for Overall Well-Being

Doctor's Best's Fully Active B12 claims to support healthy memory, mood, circulation, and overall well-being with methylcobalamin, the most biochemically active form of Vitamin B12. Vitamin B12 is crucial for human health from conception through advanced age, playing essential roles in gene regulation (epigenetics), nerve cell communication, and cysteine management to prevent endothelial cell damage. This gluten-free, non-GMO, vegetarian, and vegan supplement ensures quality and efficacy.

Organic
Product Amount180 capsules
FormCapsules

Frequently Asked Questions - Vitamin B12 Supplements

We researched commonly asked questions and concerns from users about vitamin B12. With the help of Kathy Shattler, a Registered Dietitian Nutritionist, we put together some answers.

What is the importance of vitamin B12?

Vitamin B12 is essential for health. It supports blood and nerve cells, DNA synthesis, protein metabolism, and cellular energy production. It also aids in red blood cell formation, brain function, eye health, bone cell production, and calcium metabolism. 


B12's effects on DNA, the nervous system, and energy generation are particularly important. Common deficiencies in B1, B6, and B12 highlight the need for adequate supplementation to maintain overall health.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

B12's effect on DNA, the brain and nervous system, and the generation of cellular energy are among the most important health benefits.

Is vitamin B12 safe? Does vitamin B12 have side effects or interactions with other medications?

Vitamin B12 supplements are generally safe, but interactions with medications like Metformin and aspirin can deplete B12 levels, and vitamins like folate and vitamin C can affect its absorption. To optimize absorption, take B12 separately from other vitamins or medications by at least two hours and with food like meat or dairy. High doses can cause adverse effects, especially in those with coronary stents, diabetes, or cancer risk, and pregnant or lactating women should not exceed the recommended daily allowance.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

Some medications and vitamins can deplete or interfere with B12, so take it with food separately from other pills. Avoid high doses unless recommended by a health professional, especially during pregnancy and lactation.

What form of vitamin B12 is best?

Vitamin B12 comes in four main forms: Cyanocobalamin, a synthetic and cost-effective option found in supplements; Methylcobalamin and adenosylcobalamin, natural active forms found in food, with Methylcobalamin often preferred for its direct absorption; and Hydroxocobalamin, used therapeutically in injectable form


The choice of B12 form depends on treatment goals; Methylcobalamin is favored for neurological conditions due to its effective uptake by neuronal cells, while all forms can be used for repletion, such as treating pernicious anemia.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
Methylcobalamin is often recommended for its superior absorption and effectiveness in neurological treatments, making it the preferred form for addressing conditions affecting neuronal health.

What does vitamin B12 deficiency look like?

Vitamin B12 deficiency can cause fatigue, weakness, and anemia due to its role in red blood cell formation. Neurological symptoms like numbness, memory problems, and balance issues may occur, reflecting its importance in nerve function and DNA synthesis. Mood disturbances and cognitive impairments are also common. Severe deficiencies can lead to vision problems, increased risk of macular degeneration, and bone health issues. Early recognition and supplementation are essential to maintain overall health.

Top 5 Vitamin B12 Supplement

No. 1: Garden of Life, Inc.Vitamin CodeRaw B-12

No. 2: Nature Made Nutritional ProductsNature MadeVitamin B12 Extra Strength

No. 3: Jarrow FormulasJarrow FormulasMethyl B-12 & Methyl Folate Lemon

No. 4: Naturelo Premium Supplements LLCNaturelo Vegan Vitamin B12 Supplement With Spirulina

No. 5: Amazon.com Services LLCAmazon BasicsVitamin B12 3000 mcg Gummies

View Full Ranking
The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

Most Viewed
Featured Rankings Similar to Vitamin B12 Supplements

Zinc Gummies

10 Best

Search by category

mybest

We connect users with the best tried and true products,
tested by our in-house guides and backed by expert insight.

Copyright mybest All Rights Reserved.