10 Best Probiotics for Men of 2025
More than ever, men are taking a proactive role in their gut health. Probiotics, a popular supplement with many benefits, help maintain gut health and ensure proper digestion and nutrient absorption.
Quick List - Top Probiotics for Men
Physician's Choice
A High Strength Assortment of Probiotics and Prebiotics
Megan is a registered dietitian and gluten-free food influencer (@sayimafoodie) and owns a virtual nutrition private practice–Nutrition by Megan. Currently, she works as a performance nutrition intern at the United States Naval Academy. She has been quoted for her nutrition expertise in numerous media outlets, including Health, Forbes, People, Clean Plates, EatingWell, and Eat This, Not That! Megan earned her undergraduate degree in nutritional sciences and toxicology-dietetics at the University of California, Berkeley.
With over a decade of weightlifting experience, Christopher Heffner is an avid fitness enthusiast who enjoys starting his day with a good workout. He also has a background in engineering and business, bringing a unique blend of technical knowledge and practicality to his endeavors.
The expert oversees the Buying Guide only, and does not determine the products and services featured.
Table of Contents
- Why You Can Trust Us
- How to Choose Probiotics for Men
- Look for a Blend of Key Strains for Well-Rounded Benefits1
- Consider Prebiotics to Improve Nutrient Absorption and Digestion2
- Check for 1 to 10 Billion CFUs for an Adequate Dose3
- Choose Pills for Convenience, Gummies for Taste4
- Enteric-Coated Probiotics are Most Effective5
- Ensure Quality by Looking for Supplements that are Third Party Tested6
- 10 Best Probiotics for Men Ranking
- No. 1Physician's Choice | Physician's Choice｜60 Billion Probiotic
- No. 2Culturelle | Culturelle｜Pro Strength Digestive Daily Probiotics
- No. 3NewRhythm | Probiotics 50 Billion CFU 20 Strains
- No. 4Nature's Bounty | Acidophilus Probiotic
- No. 5Wholesome Wellness | Raw Probiotics 100 Billion CFU
- 5 more products
- Possible Side Effects
- Geek Out on Gut Health
Why You Can Trust Us
Every mybest article is crafted with hours of in-depth research and interviews with experts. Each month, we are continually expanding our database of products based on our research. By emphasizing user insight and reliable information, we deliver trustworthy content to readers.
How to Choose Probiotics for Men
Look for a Blend of Key Strains for Well-Rounded Benefits
To maximize the benefits of probiotics, it's often beneficial to choose a supplement containing a blend of different strains rather than opting for a single-strain product. Each strain has unique properties and targets specific areas of gut health. Huff provides the following example: "Lactobacillus primarily colonizes the small intestine, supporting digestion and immune function, while Bifidobacterium mainly resides in the large intestine, promoting bowel regularity and reducing inflammation.
Strains of Lactobacillus and Bifidobacterium have garnered attention for their potential to support athletic performance. These beneficial bacteria also help modulate the immune system and may aid in preventing illness, indirectly benefiting physical well-being.
Consider Prebiotics to Improve Nutrient Absorption and Digestion
Check for 1 to 10 Billion CFUs for an Adequate Dose
The NIH recognizes a dosage between 1 and 10 billion Colony-Forming Units (CFUs), used to quantify live probiotic bacteria per dose, as the standard for supplements. Select a supplement containing CFUs in this range to ensure a sufficient dosage.
Choose Pills for Convenience, Gummies for Taste
Pills and capsules are ideal for those seeking a hassle-free way to add probiotics to their regimen. Huff also points out the portability of pills for those with busy schedules. Additionally, probiotics in pill form tend to provide the best value.
Gummies are a comparatively new format compared to pills. However, they are popular due to their palatable taste and texture, especially for those who don't like swallowing pills. Our registered dietitian also points out that less research has been conducted on gummies than on pills and capsules.
Enteric-Coated Probiotics are Most Effective
Enteric coatings help ensure that probiotics reach the intestine without being inactivated by stomach acid.
Ensure Quality by Looking for Supplements that are Third Party Tested
Third-party testing certifications are essential to ensure supplement quality and efficacy.
When selecting a probiotic supplement, it is crucial to choose a reputable brand that adheres to high-quality standards. Choose products that have undergone third-party testing. Huff recommends that users look for labels from organizations that include Informed Choice, USP, and NSF Certified for Sport. These certifications ensure that the product meets specific quality and purity standards.
10 Best Probiotics for Men Ranking
Products | Image | Click to purchase | Key features | Details | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lactobacillus | Bifidobacterium | Probiotic Blend | Prebiotics | CFUs per Serving | Servings | Form | Acid-Resistant Coating | Third Party Certifications | |||||
1 | Physician's Choice Physician's Choice｜60 Billion Probiotic | | A High Strength Assortment of Probiotics and Prebiotics | 60 Billion CFUs | 30 Servings | Pill/Capsule | None | ||||||
2 | Culturelle Culturelle｜Pro Strength Digestive Daily Probiotics | | An Extra-Strength Single Strain | 12 Billion CFUs | 60 Servings | Pill/Capsule | CDHF Certified | ||||||
3 | NewRhythm Probiotics 50 Billion CFU 20 Strains | | 50 Billion CFUs of 20 Strains | 50 Billion CFUs | 30 Servings | Pill/Capsule | None | ||||||
4 | Nature's Bounty Acidophilus Probiotic | | 100 Million CFUs of Pure Lactobacillus Acidophilus | 100 Million CFUs | 100 Servings | Pill/Capsule | GMP, CDHF, and USDA organic | ||||||
5 | Wholesome Wellness Raw Probiotics 100 Billion CFU | | 3 Trillion CFUs per Bottle | 100 Billion CFUs | 30 Servings | Pill/Capsule | FDA, NSF, and GMP certified | ||||||
6 | Garden of Life Once Daily Men's Probiotics | | 15 Probiotic Strains Formulated for Men | 50 Billion CFUs | 30 Servings | Pill/Capsule | Informed Choice, NSF | ||||||
7 | BioCodex Florastor｜Daily Probiotic Supplement | | Strengthening Digestive and Immune Health Naturally | 50 Servings | Pill/Capsule | GMP, ANSM | |||||||
8 | NOW Foods Probiotic-10 25 Billion | | Dairy, Soy, and Gluten-Free | 25 Billion CFUs | 100 Servings | Pill/Capsule | Intertek GMP, Informed-Sport | ||||||
9 | Earth's Pearl Probiotic + Prebiotic | | 4 Billion Easy to Swallow CFUs | 4 Billion CFUs | 60 Servings | Pill/Capsule | GMP, NSF | ||||||
10 | Align Align｜24/7 Digestive Support*§ Probiotic Supplement | | A Supplement Containing Only Bifidobacterium Infantus | 1 Billion CFUs | 63 Servings | Pill/Capsule | None | ||||||
Physician's ChoicePhysician's Choice ｜ 60 Billion Probiotic
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 60 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- None
A High Strength Assortment of Probiotics and Prebiotics
This is a high-potency probiotic containing 10 different strains (including Bifidobacterium and Lactobacillus) and prebiotics in a time-release capsule. As the name implies, it includes six times our recommended per-serving dose of CFUs. Many customers have reported improved digestion, reduced bloating, and a stronger immune system (becoming sick less often and with less severity).
| Servings | 30 Servings |
|---|
CulturelleCulturelle ｜ Pro Strength Digestive Daily Probiotics
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 12 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- CDHF Certified
An Extra-Strength Single Strain
This supplement features a single probiotic strain (12 billion CFUs of Lactobacillus rhamnosus) specifically chosen for its digestive health benefits. Culturelle claims they referenced “over 1000 scientific studies” when selecting their probiotic strain. Customers have reported relief from common digestive issues like bloating, gas, and constipation. Some users have mentioned that the blister packaging makes it more convenient to bring these pills when traveling.
| Servings | 60 Servings |
|---|
NewRhythmProbiotics 50 Billion CFU 20 Strains
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 50 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- None
50 Billion CFUs of 20 Strains
This supplement from NewRhythm combines 50 billion CFUs of probiotics and prebiotics to support gut health and overall well-being. The probiotic strains used are focused on different varieties of Bifidobacterium and Lactobacillus. Customers appreciate the convenient, stomach-acid-resistant capsule form and the noticeable improvement in digestion and energy levels that they provide.
| Servings | 30 Servings |
|---|
Nature's BountyAcidophilus Probiotic
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 100 Million CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- GMP, CDHF, and USDA organic
100 Million CFUs of Pure Lactobacillus Acidophilus
| Servings | 100 Servings |
|---|
Wholesome WellnessRaw Probiotics 100 Billion CFU
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 100 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- FDA, NSF, and GMP certified
3 Trillion CFUs per Bottle
| Servings | 30 Servings |
|---|
Garden of LifeOnce Daily Men's Probiotics
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 50 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- Informed Choice, NSF
15 Probiotic Strains Formulated for Men
This supplement from Garden of Life is specifically formulated for men's health, supporting digestive and immune function. It features 35 billion CFUs of Lactobacillus and 15 billion CFUs of Bifidobacterium per capsule. It also contains a blend of prebiotic fibers. Customers appreciate the convenient once-daily dosage and the noticeable improvement in digestion and overall well-being.
| Servings | 30 Servings |
|---|
BioCodexFlorastor ｜ Daily Probiotic Supplement
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- GMP, ANSM
Strengthening Digestive and Immune Health Naturally
Florastor's Daily Probiotic Supplement offers dual-action support for digestive and immune health. This probiotic supplement contains 250mg of the exclusive probiotic strain Saccharomyces boulardii, which has been extensively researched for over 65 years.
It helps strengthen digestive support by flushing out bad bacteria and promoting the growth of good bacteria. By breaking down carbs and sugars, Florastor improves digestion and supports immune health. These easy-to-take capsules are suitable for both men and women and can be taken at the same time as antibiotics, making them a convenient choice for maintaining gut health.
| Servings | 50 Servings |
|---|
NOW FoodsProbiotic-10 25 Billion
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 25 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- Intertek GMP, Informed-Sport
Dairy, Soy, and Gluten-Free
| Servings | 100 Servings |
|---|
Earth's PearlProbiotic + Prebiotic
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 4 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- GMP, NSF
4 Billion Easy to Swallow CFUs
| Servings | 60 Servings |
|---|
AlignAlign ｜ 24/7 Digestive Support*§ Probiotic Supplement
| Lactobacillus | |
|---|---|
| Bifidobacterium | |
| Probiotic Blend | |
| Prebiotics | |
| CFUs per Serving | 1 Billion CFUs |
- Form
- Pill/Capsule
- Acid-Resistant Coating
- Third Party Certifications
- None
A Supplement Containing Only Bifidobacterium Infantus
This proprietary single-strain probiotic from Align focuses on digestive health. Customers often report relief from digestive issues like bloating, gas, and constipation. However, some users find the price point a bit high for a supplement containing a two-month supply of pills containing only 1 billion CFUs per serving.
| Servings | 63 Servings |
|---|
Possible Side Effects
Geek Out on Gut Health
Top 5 Probiotics for Men
No. 1: Physician's Choice｜Physician's Choice｜60 Billion Probiotic
No. 2: Culturelle｜Culturelle｜Pro Strength Digestive Daily Probiotics
No. 3: NewRhythm｜Probiotics 50 Billion CFU 20 Strains
No. 4: Nature's Bounty｜Acidophilus Probiotic
No. 5: Wholesome Wellness｜Raw Probiotics 100 Billion CFU
View Full RankingThe descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.
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