10 Best Probiotic Supplements [Registered Dietitian-Reviewed Buying Guide]

This is a high-potency probiotic containing 10 different strains (including Bifidobacterium and Lactobacillus) and prebiotics in a time-release capsule. As the name implies, it includes six times our recommended per-serving dose of CFUs. Many customers have reported improved digestion, reduced bloating, and a stronger immune system (becoming sick less often and with less severity).

Garden of Life's Dr. Formulated Probiotics Once Daily Women's is tailored to meet women's specific digestive and immune needs. With 50 billion CFU and 16 diverse probiotic strains in each capsule, including clinically studied strains like L. reuteri and L. fermentum, this supplement provides comprehensive support. 

Additionally, this formula includes a whole food prebiotic fiber blend to nourish the growth of beneficial bacteria. With a focus on supporting vaginal health, this probiotic helps maintain a healthy balance of gut flora and pH levels, which is crucial for immune system function, digestive health, and overall well-being. 

This supplement features a single probiotic strain (12 billion CFUs of Lactobacillus rhamnosus) specifically chosen for its digestive health benefits. Culturelle claims they referenced “over 1000 scientific studies” when selecting their probiotic strain. Customers have reported relief from common digestive issues like bloating, gas, and constipation. Some users have mentioned that the blister packaging makes it more convenient to bring these pills when traveling.

This supplement from NewRhythm combines 50 billion CFUs of probiotics and prebiotics to support gut health and overall well-being. The probiotic strains used are focused on different varieties of Bifidobacterium and Lactobacillus. Customers appreciate the convenient, stomach-acid-resistant capsule form and the noticeable improvement in digestion and energy levels that they provide.

OLLY Probiotic + Prebiotic gummies contain Bacillus coagulans, a resilient strain of probiotics that can support digestive health and immune function. Combined with prebiotic fiber, these gummies help nourish the good bacteria in your gut, promoting better digestion and overall gut balance.

With no artificial flavors or colors, these peach-flavored gummies are gluten-free and easy to incorporate into your daily routine. They offer a convenient, chewable option for individuals who prefer not to take capsules or powders, making them a popular choice for both gut health and immune support.

Florastor's Daily Probiotic Supplement offers dual-action support for digestive and immune health. This probiotic supplement contains 250mg of the exclusive probiotic strain Saccharomyces boulardii, which has been extensively researched for over 65 years. 

It helps strengthen digestive support by flushing out bad bacteria and promoting the growth of good bacteria. By breaking down carbs and sugars, Florastor improves digestion and supports immune health. These easy-to-take capsules are suitable for both men and women and can be taken at the same time as antibiotics, making them a convenient choice for maintaining gut health.

Amazon Basics Prebiotic & Probiotic Gummies combine chicory fiber prebiotics with 2 billion CFU of probiotics per serving to support both gut health and digestion. The chicory fiber feeds beneficial bacteria, while the probiotics help maintain a balanced microbiome. The combination of these ingredients may help ease digestive discomfort and promote regularity.

These gummies are vegetarian, gluten-free, and blue raspberry-flavored, making them a simple and tasty option for daily gut health support. They are also pectin-based, which can be beneficial for those who prefer plant-based ingredients.

Acidophilus Probiotic from Nature’s Bounty is formulated to support both digestive and immune health by providing friendly bacteria. Each tablet contains 100 million active Lactobacillus Acidophilus cultures, which are guaranteed through expiration. This probiotic strain is naturally found in the intestinal tract, making it a beneficial addition to your daily routine. 

To help maintain a healthy gut flora balance, simply take one tablet daily, preferably with a meal. This supplement is also gluten-free, dairy-free, and wheat-free, making it suitable for vegetarians and those with dietary restrictions.

This proprietary single-strain probiotic from Align focuses on digestive health. Customers often report relief from digestive issues like bloating, gas, and constipation. However, some users find the price point a bit high for a supplement containing a two-month supply of pills containing only 1 billion CFUs per serving.

Garden of Life's Dr. Formulated Probiotics Prostate+ is a comprehensive supplement designed to support prostate, digestive, and immune health. With 50 billion CFU, 15 probiotic strains, 500mg of organic cranberry, 440mg of organic prebiotic fiber, and 1,000 IU of Vitamin D3, this formula provides targeted support in just two capsules a day. 

Backed by science, Prostate+ includes B. animalis subsp. lactis and other clinically studied ingredients to promote lower urinary tract and prostate health as men age. The inclusion of organic cranberry, prebiotics, and Vitamin D3 further enhances its effectiveness. This doctor-formulated supplement offers a holistic approach to men's health, supporting overall well-being.