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Probiotic SupplementsHelping You Find the Best
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Probiotic SupplementsHelping You Find the Best
  • 10 Best Probiotics for Travel of 2025 1
  • 10 Best Probiotics for Travel of 2025 2
  • 10 Best Probiotics for Travel of 2025 3
  • 10 Best Probiotics for Travel of 2025 4
  • 10 Best Probiotics for Travel of 2025 5

10 Best Probiotics for Travel of 2025

Traveling to a new destination can be an exciting adventure, but it can also be taxing on your digestive system. Exposure to different foods, water sources, and bacteria can lead to traveler's diarrhea and other gastrointestinal issues. 
We’ve consulted Registered Dietitian Katie Drakeford to bring you the most helpful information for our guide on choosing a probiotic to help ease your ailments on the road. We’ve also compiled our ranking of the top 10 probiotics for travel, selected from among the best-selling options available on Amazon, to get you started on your search.
Last updated 02/20/2025

Quick List - Top Probiotics for Travel

1

Physician's Choice

Physician's Choice60 Billion Probiotic
60 Billion Probiotic

A High Strength Assortment of Probiotics and Prebiotics

2

Garden of Life

Dr. Formulated ProbioticsOnce Daily Women's
Once Daily Women's

Nourish Your Gut, Empower Your Health

3

BioCodex

FlorastorDaily Probiotic Supplement
Daily Probiotic Supplement

Strengthening Digestive and Immune Health Naturally

4

NewRhythm

Probiotics 50 Billion CFU 20 Strains
Probiotics 50 Billion CFU 20 Strains

50 Billion CFUs of 20 Strains

5

Culturelle

Digestive Daily Probiotic
Digestive Daily Probiotic

A Single-Strain Probiotic and Prebiotic

Katie Drakeford
Expert
Registered Dietitian
Katie Drakeford

Katie Drakeford, MA, RD, CSP, LD, CLC, is a Registered Dietitian with over 12 years of experience serving all ages across the lifespan, from critically ill neonates to aging populations. She holds a board certification in pediatric nutrition and serves as a subject matter expert on the Academy of Nutrition and Dietetics pediatric exam committee. She attended the University of Oklahoma Health Sciences Center, where she received a Master’s in Dietetics and completed her Dietetic Internship.

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Christopher Heffner
Guide
Content Planner at mybest
Christopher Heffner

With over a decade of weightlifting experience, Christopher Heffner is an avid fitness enthusiast who enjoys starting his day with a good workout. He also has a background in engineering and business, bringing a unique blend of technical knowledge and practicality to his endeavors.

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The expert oversees the Buying Guide only, and does not determine the products and services featured.

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Why Take Probiotics When Traveling?

Expert
Expert

Probiotics are a great tool for travelers who are hoping to boost immunity and prevent traveler's diarrhea.

Why Take Probiotics When Traveling?
Probiotics can help alleviate a range of travel-related digestive woes. They are most commonly used to prevent and manage traveler's diarrhea, a frequent complaint caused by consuming contaminated food or water. Beyond this, probiotics may ease other digestive disturbances like bloating, constipation, and general stomach upset that can arise from changes in diet and routine. Probiotics can contribute to a more comfortable and enjoyable travel experience by bolstering your gut's microbial balance.

How to Choose Probiotics for Travel

By understanding the key factors to consider when choosing a probiotic, you can select the right product to support your gut health and minimize the risk of travel-related digestive issues.
1

Consider the Strain

The effectiveness of a probiotic hinges on the specific strains of bacteria it contains; different strains offer varying benefits.

Look for a Strain That Is Effective Against Traveler’s Diarrhea

Expert
Expert

L. acidophilus, L. rhamnosus, L. fermentum, Saccharomyces cerevisiae, and S. boulardii may all be useful in preventing traveler's diarrhea.

Look for a Strain That Is Effective Against Traveler’s Diarrhea

Saccharomyces boulardii is specifically recognized for its efficacy against traveler's diarrhea. If your primary concern is preventing this common ailment, prioritize a probiotic containing this strain.

Choose a Blend of Strains to be Ready for Anything

Expert
Expert

Some strains may be more effective at reducing traveler's diarrhea, so getting a probiotic with a variety of strains is a good strategy.

Choose a Blend of Strains to be Ready for Anything

A multi-strain probiotic can offer broader protection. A combination of Lactobacillus and Bifidobacterium strains can be advantageous, as they address various causes of digestive upset, offering a more comprehensive approach to gut health maintenance while traveling.

2

Look for at Least 10 Billion CFUs for an Adequate Dose

Expert
Expert

10 billion CFUs is a fairly standard probiotic dose.

Look for at Least 10 Billion CFUs for an Adequate Dose

CFU, or Colony Forming Units, represents the number of live bacteria in each dose. To ensure effectiveness for travel purposes, a probiotic with at least 10 billion CFUs is generally recommended.

3

Choose a Probiotic That Doesn’t Require Refrigeration So It Can Stay In Your Luggage

Expert
Expert

While traveling, it's important to have a convenient product that does not require refrigeration. If not stored properly, the bacteria may not be viable.

Choose a Probiotic That Doesn’t Require Refrigeration So It Can Stay In Your Luggage

Travel often involves fluctuating temperatures and limited access to refrigeration. Opt for a shelf-stable probiotic that doesn't require refrigeration. This ensures the bacteria remain viable and effective, regardless of storage conditions.

4

Choose an Age-Appropriate Dose

Expert
Expert
Research also supports the use of probiotics for children for the treatment of infectious diarrhea and can reduce symptoms by up to 1 day.
Choose an Age-Appropriate Dose
Probiotic needs vary depending on age. ​​Always select a product with a recommended dosage suitable for the traveler(s) taking it, whether an adult or a child, throughout the various stages of their development. As always, it’s best to consult a pediatrician before giving probiotics to young children.
5

Consider the Form

Expert
Expert

Probiotics in pill or capsule form can be thrown in your bag without worrying about special storage or spills.

Consider the Form

Independent of the strains used, probiotics come in various forms with advantages and disadvantages, especially regarding travel and who you're traveling with.


  • Pills and capsules are the most portable and convenient options for travel. Their compact size makes them easy to pack in any suitcase or carry-on, taking up minimal space. They won't cause any trouble with the TSA if you only bring a carry-on. They also offer a precise and consistent dosage, eliminating any guesswork. Consider capsules over tablets if you have difficulty swallowing pills. Look for individually blister-packed pills or capsules, which protect the probiotics from moisture and degradation, especially in humid climates.

  • Gummies can make probiotics more palatable for children, thus reducing the likelihood of picky eaters refusing their supplements. However, ensure the gummy formulation is shelf-stable, as many gummies require refrigeration. Carefully check the label to confirm it contains the appropriate strains and CFU count for your child's age. Be aware that gummies may contain added sugars and artificial colors, so look for options with minimal additives if possible. Also, keep in mind that gummies might melt in extremely hot climates.

  • Liquid probiotics allow for more flexible dosing, which can help adjust intake based on individual needs or digestive issues. However, they may be less convenient to pack and sometimes require refrigeration (so check the label).
6

Look for Prebiotics for Additional Immune Support

Expert
Expert

Probiotics help boost the immune system by creating unfavorable conditions for harmful bacteria to grow and thrive.

Look for Prebiotics for Additional Immune Support

Prebiotics are non-digestible fibers that feed the beneficial bacteria in your gut. Probiotics can also create antimicrobial compounds and reduce bacterial adhesion. Combining probiotics with prebiotics can enhance their effectiveness and provide additional support for your immune system, particularly during travel.

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10 Best Probiotics for Travel Ranking

To help you stay healthy and comfortable during your travels, we've compiled a list of the top 10 probiotics for travel, ranked according to the essential criteria in our buying guide.
Popularity
Filter
Products
Image
Click to purchase
Key features
Details
CFUs
Strains
Probiotic Strain
Non-Refrigerated
Age Groups
Form
Prebiotics
Servings per Container
1

Physician's Choice

Physician's Choice60 Billion Probiotic

Physician's Choice 60 Billion Probiotic 1

A High Strength Assortment of Probiotics and Prebiotics

60 Billion

10

Lactobacillus Acidophilus、Bifidobacterium Infantus

18+

Capsules

30

2

Garden of Life

Dr. Formulated ProbioticsOnce Daily Women's

Garden of Life Once Daily Women's 1

Nourish Your Gut, Empower Your Health

50 Billion

16

Lactobacillus Acidophilus、Bifidobacterium Infantus

18+

Capsules

30

3

BioCodex

FlorastorDaily Probiotic Supplement

BioCodex Daily Probiotic Supplement 1

Strengthening Digestive and Immune Health Naturally

unknown

1

Saccharomyces Boulardi

4+

Capsules

50

4

NewRhythm

Probiotics 50 Billion CFU 20 Strains

NewRhythm Probiotics 50 Billion CFU 20 Strains 1

50 Billion CFUs of 20 Strains

50 Billion

20

Lactobacillus Acidophilus、Bifidobacterium Infantus

18+

Capsules

30

5

Culturelle

Digestive Daily Probiotic

Culturelle Digestive Daily Probiotic 1

A Single-Strain Probiotic and Prebiotic

10 Billion

1

18+

Capsules

30

6

Microbiome Labs

MegaSporeBiotic

Microbiome Labs MegaSporeBiotic 1

Formulated to Survive High Temperatures

4 Billion

5

5+

Capsules

60

7

Vitalitown

Probiotics 120 Billion CFUs

Vitalitown Probiotics 120 Billion CFUs 1

The Most CFUs and Strains

120 Billion

36

Lactobacillus Acidophilus、Bifidobacterium Infantus

unknown

Capsules

30

8

ZBiotics

Pre-Alcohol

ZBiotics Pre-Alcohol 1

A Probiotic to Prepare You for a Night Out

1

18+

Liquid

0.5 fl oz

9

Mary Ruth's

Organic Liquid Probiotic

Mary Ruth's Organic Liquid Probiotic 1

A Liquid Probiotic for the Whole Family

2 Billion

13

Lactobacillus Acidophilus、Bifidobacterium Infantus

Kid, Adult

Liquid

20

10

Vitafusion

Probiotic Gummy Supplements

Vitafusion Probiotic Gummy Supplements 1

Gummies Made in the USA

5 Billion

2

unknown

18+

Gummies

70

If you don't see the product you're looking for, you can request that it be listed.
No.1

Physician's Choice
Physician's Choice60 Billion Probiotic

60 Billion Probiotic 1
Source:amazon.com
60 Billion Probiotic 2
Source:amazon.com
Lowest price
$23.97
Mid
Lowest price
$23.97
Mid
CFUs60 Billion
Strains10
Probiotic StrainLactobacillus Acidophilus、Bifidobacterium Infantus
Non-Refrigerated
Form
Capsules
Prebiotics

A High Strength Assortment of Probiotics and Prebiotics

This is a high-potency probiotic containing 10 different strains (including Bifidobacterium and Lactobacillus) and prebiotics in a time-release capsule. As the name implies, it includes six times our recommended per-serving dose of CFUs. Many customers have reported improved digestion, reduced bloating, and a stronger immune system (becoming sick less often and with less severity).

Age Groups18+
Servings per Container30
Was this Ranking helpful?
No.2

Garden of Life
Dr. Formulated ProbioticsOnce Daily Women's

Lowest price
$33.05
High Mid
CFUs50 Billion
Strains16
Probiotic StrainLactobacillus Acidophilus、Bifidobacterium Infantus
Non-Refrigerated
Form
Capsules
Prebiotics

Nourish Your Gut, Empower Your Health

Garden of Life's Dr. Formulated Probiotics Once Daily Women's is tailored to meet women's specific digestive and immune needs. With 50 billion CFU and 16 diverse probiotic strains in each capsule, including clinically studied strains like L. reuteri and L. fermentum, this supplement provides comprehensive support. 


Additionally, this formula includes a whole food prebiotic fiber blend to nourish the growth of beneficial bacteria. With a focus on supporting vaginal health, this probiotic helps maintain a healthy balance of gut flora and pH levels, which is crucial for immune system function, digestive health, and overall well-being. 

Age Groups18+
Servings per Container30
No.3

BioCodex
FlorastorDaily Probiotic Supplement

Lowest price
$62.06
High
CFUsunknown
Strains1
Probiotic StrainSaccharomyces Boulardi
Non-Refrigerated
Form
Capsules
Prebiotics

Strengthening Digestive and Immune Health Naturally

Florastor's Daily Probiotic Supplement offers dual-action support for digestive and immune health. This probiotic supplement contains 250mg of the exclusive probiotic strain Saccharomyces boulardii, which has been extensively researched for over 65 years. 


It helps strengthen digestive support by flushing out bad bacteria and promoting the growth of good bacteria. By breaking down carbs and sugars, Florastor improves digestion and supports immune health. These easy-to-take capsules are suitable for both men and women and can be taken at the same time as antibiotics, making them a convenient choice for maintaining gut health.

Age Groups4+
Servings per Container50
No.4

NewRhythm
Probiotics 50 Billion CFU 20 Strains

Lowest price
$16.99
Low Mid
CFUs50 Billion
Strains20
Probiotic StrainLactobacillus Acidophilus、Bifidobacterium Infantus
Non-Refrigerated
Form
Capsules
Prebiotics

50 Billion CFUs of 20 Strains

This supplement from NewRhythm combines 50 billion CFUs of probiotics and prebiotics to support gut health and overall well-being. The probiotic strains used are focused on different varieties of Bifidobacterium and Lactobacillus. Customers appreciate the convenient, stomach-acid-resistant capsule form and the noticeable improvement in digestion and energy levels that they provide.

Age Groups18+
Servings per Container30
No.5

Culturelle
Digestive Daily Probiotic

Lowest price
$17.47
Low Mid
CFUs10 Billion
Strains1
Probiotic Strain
Non-Refrigerated
Form
Capsules
Prebiotics

A Single-Strain Probiotic and Prebiotic

Culturelle Digestive Daily Probiotic features 10 billion CFUs of Lactobacillus GG, a well-researched strain supporting digestive health and immune function. This single-strain probiotic is specifically designed to help maintain a healthy balance of gut bacteria, promoting regular digestion and alleviating occasional discomfort. Culturelle is a trusted brand with a long history of providing high-quality probiotics. It also contains 200mg of inulin prebiotics.

Age Groups18+
Servings per Container30
No.6

Microbiome Labs
MegaSporeBiotic

Lowest price
$64.99
High
CFUs4 Billion
Strains5
Probiotic Strain
Non-Refrigerated
Form
Capsules
Prebiotics

Formulated to Survive High Temperatures

Microbiome Labs MegaSporeBiotic introduces a unique approach to gut health by utilizing a spore-based probiotic. Spore-forming bacteria are highly resilient, capable of surviving the harsh conditions of the stomach and reaching the intestines effectively. This heat resistance also makes it suitable for travel. This product features Bacillus subtilis HU58, which Microbiome Labs claims will help to diversify the gut microbiome and support digestive balance.

Age Groups5+
Servings per Container60
No.7

Vitalitown
Probiotics 120 Billion CFUs

Lowest price
$24.00
Mid
CFUs120 Billion
Strains36
Probiotic StrainLactobacillus Acidophilus、Bifidobacterium Infantus
Non-Refrigerated
Form
Capsules
Prebiotics

The Most CFUs and Strains

Vitalitown Probiotics 120 Billion CFUs offers a high-potency formula containing a hefty dose of a diverse blend of 36 probiotic strains. This extensive array of bacteria provides broad-spectrum support for gut health, addressing various digestive concerns. The inclusion of prebiotics and digestive enzymes further enhances the supplement's effectiveness. 


The delayed-release capsules ensure the probiotics reach the intestines intact, maximizing their impact. This product is ideal for individuals seeking a comprehensive and high-potency probiotic to provide overall digestive well-being or fast-acting stomach support while traveling.

Age Groupsunknown
Servings per Container30
No.8

ZBiotics
Pre-Alcohol

Lowest price
$36.00
High Mid
CFUs
Strains1
Probiotic Strain
Non-Refrigerated
Form
Liquid
Prebiotics

A Probiotic to Prepare You for a Night Out

ZBiotics Pre-Alcohol is a unique probiotic supplement designed to prepare the body for alcohol consumption. This innovative formula features specific strains of bacteria that can help to metabolize alcohol more efficiently, potentially reducing the severity of hangovers. By supporting the liver's natural detoxification processes, ZBiotics Pre-Alcohol can help individuals enjoy occasional alcohol consumption with less discomfort.

Age Groups18+
Servings per Container0.5 fl oz
No.9

Mary Ruth's
Organic Liquid Probiotic

Lowest price
$21.95
Low Mid
CFUs2 Billion
Strains13
Probiotic StrainLactobacillus Acidophilus、Bifidobacterium Infantus
Non-Refrigerated
Form
Liquid
Prebiotics

A Liquid Probiotic for the Whole Family

Mary Ruth's Organic Liquid Probiotic is a shelf-stable liquid formulation that provides a convenient and easily absorbable way to supplement your gut health. This organic formula features a blend of beneficial bacteria, including Lactobacillus acidophilus and Bifidobacterium lactis. The liquid format makes it easy to adjust dosages, especially for children. This product suits those seeking a convenient and easily digestible probiotic option. Since dosage is controlled by the dropper, it is easy to administer the correct amount to anyone in your family.

Age GroupsKid, Adult
Servings per Container20
No.10

Vitafusion
Probiotic Gummy Supplements

Lowest price
$22.99
Mid
CFUs5 Billion
Strains2
Probiotic Strain
Non-Refrigerated
unknown
Form
Gummies
Prebiotics

Gummies Made in the USA

Vitafusion Probiotic Gummy Supplements make it easy and enjoyable to support gut health. These delicious gummies provide a fun and convenient way for adults and children to consume daily probiotics. Each gummy delivers a blend of two probiotic strains, making it a pleasant and effective way to maintain gut health. Be aware that each serving does contain 3g of added sugars.

Age Groups18+
Servings per Container70

Top 5 Probiotics for Travel

No. 1: Physician's ChoicePhysician's Choice60 Billion Probiotic

No. 2: Garden of LifeDr. Formulated ProbioticsOnce Daily Women's

No. 3: BioCodexFlorastorDaily Probiotic Supplement

No. 4: NewRhythmProbiotics 50 Billion CFU 20 Strains

No. 5: CulturelleDigestive Daily Probiotic

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The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

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