mybest
Vitamin D3 and K2 SupplementsHelping You Find the Best
mybest
Vitamin D3 and K2 SupplementsHelping You Find the Best
  • 10 Best Vitamin D3 and K2 Supplements  [Registered Dietitian-Reviewed] 1
  • 10 Best Vitamin D3 and K2 Supplements  [Registered Dietitian-Reviewed] 2
  • 10 Best Vitamin D3 and K2 Supplements  [Registered Dietitian-Reviewed] 3
  • 10 Best Vitamin D3 and K2 Supplements  [Registered Dietitian-Reviewed] 4
  • 10 Best Vitamin D3 and K2 Supplements  [Registered Dietitian-Reviewed] 5

10 Best Vitamin D3 and K2 Supplements [Registered Dietitian-Reviewed]

Vitamin D3 and K2 supplements are excellent for supporting bone and cardiovascular health. These vitamins work synergistically to enhance calcium absorption and direct it to where it's needed — your bones — while preventing arterial calcification. 

For this comprehensive guide, we teamed up with registered dietitian nutritionist Kathy Shattler. Our team also put together a ranking of the best vitamin D3 and K2 supplements in the U.S. to get you started on your search. From flexible liquid options to softgels with added absorption enhancers like coconut oil, we’ll highlight the top products on the market to fit your specific needs. Whether you aim to maintain bone density, support heart health, or avoid the side effects of over-supplementation, this guide will steer you toward the right solution.

Last updated 11/29/2024

Quick List - Top Vitamin D3 and K2 Supplement

1

Sports Research

Vitamin D3 + K2 with Coconut MCT Oil
Vitamin D3 + K2 with Coconut MCT Oil

Plant-Based Power for Bone and Heart Health

2

Dr. Berg

D3 & K2 Vitamin (10,000 IU)
D3 & K2 Vitamin (10,000 IU)

Advanced Formula for Superior Absorption

3

Micro Ingredients

Micro IngredientsVitamin D3 K2 Supplement Softgels
Vitamin D3 K2 Supplement Softgels

High-Potency D3 and MK-7 K2 with MCT Oil for Maximum Absorption

4

Bronson

BronsonVitamin K2 MK-7 Plus Vitamin D3
Vitamin K2 MK-7 Plus Vitamin D3

Advanced Bone and Heart Health Support

5

Nature Made

Nature MadeVitamin D3 + K2 Softgels
Vitamin D3 + K2 Softgels

K2 and D3 for Enhanced Calcium Utilization and Artery Health

Kathy Shattler, MS, RDN
Expert
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

A Registered Dietitian Nutritionist for over 25 years, Kathy has mastered numerous medical specialties and teaching methods: health promotion, counseling, academic teaching, endocrinology, psychiatry/mental health, supplements, diabetes, obesity, heart disease, aging, and alternative medicine. Experiences include: -Managing her own telehealth/nutrition consulting business -Directing a continuing education program for RDs and nurses -Consulting for long-term care regulatory affairs -Working with State and local health departments -Coordinating diabetes education programs Her experiences led her to reach people with life-changing information as a medical editor and writer. For over five years, Kathy has acquired increasingly complex roles. Passionate about the root causes of disease, she obtained her certification in Integrative Medicine and Functional Nutrition from the Academy of Nutrition and Dietetics three years ago. This series continues to influence her approach to writing.

Kathy Shattler, MS, RDN's Profile
…Continue reading
mybest US Editors
Guide
Editing Dept.
mybest US Editors

mybest US' editing team consists of experienced members who have backgrounds in writing, editing, translation, and more. We are dedicated to researching what makes a product or service the best to users in the US in order to create top-quality articles. From skincare, to kitchen appliances, and to DIY supplies, our mission is to find the best ones for you.

mybest US Editors's Profile
…Continue reading
The expert oversees the Buying Guide only, and does not determine the products and services featured.

Table of Contents

Should You Take Vitamin D3 and K2 Together?

Expert
Expert

Supplementing with vitamins D3 and K2 may synergistically support cardiovascular and bone health by improving calcium metabolism and preventing vascular calcification.

Taking vitamin D3 and K2 together is generally recommended, as these two fat-soluble vitamins work synergistically to support bone health and prevent conditions like osteoporosis. Vitamin D3 helps your body absorb calcium from your diet, ensuring sufficient amounts of this essential mineral are available in the bloodstream. 


However, without vitamin K2, the calcium absorbed by D3 may not be directed appropriately, potentially leading to calcification in soft tissues, such as the arteries. K2 is critical in ensuring that calcium is deposited in the bones where it is needed rather than in the arteries. This helps promote strong bones while preventing calcium buildup in unwanted areas.


Additionally, the combination of D3 and K2 is beneficial for cardiovascular health. Vitamin K2 inhibits arterial calcification and arterial stiffening by activating matrix GLA protein (MGP), a key inhibitor of calcium deposits on the artery walls. Adequate K2 intake can, therefore, lower the risk of vascular damage, promoting better arterial health.


This combination also has additional benefits for individuals with type 2 diabetes, as studies suggest that D3 and K2 together can improve insulin action in overweight patients, helping manage blood sugar levels and reduce associated health risks.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
In a recent study, vitamin D supplementation did not lower glycemia, while vitamin K significantly affected glycemic regulation in another study. Joint supplementation may aid glycemic control secondary to the presence of vitamin K.

How to Choose Vitamin D3 and K2 Supplements - Buying Guide

Here are the points to keep in mind when choosing the best vitamin D3 and K2 supplement for you.
1

Check the Dosage: A Balanced Supplement Should Offer a D3 to K2 Ratio of Around 1,000:10

Expert
Expert
For every 5,000 IU of D3, it's recommended to take 50 mcg of vitamin K2, though some populations may require more K2 based on studies.
Check the Dosage: A Balanced Supplement Should Offer a D3 to K2 Ratio of Around 1,000:10

The recommended daily dosage of vitamin D3 and K2 supplements can vary based on individual needs. 


According to Poland's 2023 vitamin D guidelines, general recommendations from this report now suggest taking 1,000-2,000 IU of vitamin D3 daily


For vitamin K, the National Institutes of Health (NIH) recommends that men consume 120 mcg of vitamin K daily, while women need 90 mcg


There is no strict ratio for D3 to K2 intake, as individual vitamin D requirements differ. However, common suggestions are to take 10 mcg of K2 for every 1,000 IU of D3 (or 50 mcg of K2 for every 5,000 IU of D3). This ratio helps support calcium balance and cardiovascular health.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN

Vascular calcification (VC), common in end-stage kidney disease and linked to K2 depletion, was reduced by 360 mcg of K2 daily in over 61% of dialysis patients, while postmenopausal women showed arterial stiffness improvement with just 180 mcg.


The results of these studies indicate that outcomes are responsive to varying dosages of vitamin K2, which may differ based on the medical condition of the population being treated.

2

Select the Form of K2 with the Benefits You Seek

Choose the form of K2 that offers the desired health benefits. Each form offers unique advantages, so selecting the right one depends on your health goals.

Choose MK-7 (Menaquinone-7) for the Most Bioavailable and Effective Form of K2

Expert
Expert
MK-7 is longer-lasting and contributes to increasing blood levels of vitamin K, effectively showing good bioavailability compared to other forms, such as MK-4.
Choose MK-7 (Menaquinone-7) for the Most Bioavailable and Effective Form of K2
Source:amazon.com

MK-7 is the most bioavailable and longest-lasting form of K2, meaning it stays in the bloodstream longer, allowing for more effective calcium regulation. This form is particularly beneficial for older adults or postmenopausal women at a higher risk of bone density loss or osteoporosis. MK-7 helps direct calcium to the bones and away from arteries, reducing the likelihood of calcium deposits in arteries that can lead to cardiovascular issues.


MK-7 is also ideal for those seeking long-term health benefits with less frequent dosing. Since it remains active in the body longer than the MK-4 form, individuals can maintain consistent levels of K2 with a once-daily supplement. 


Individuals concerned about heart health, especially those with a family history of heart disease or arterial calcification, should opt for MK-7 to ensure their calcium is properly utilized and does not contribute to arterial plaque buildup.


There are two forms of MK-7, cis and trans, and the label should differentiate which form is being used. You should opt for the trans form of this supplement. The cis form is cheaper, but the trans form entirely determines therapeutic effectiveness.

Pick MK-4 (Menaquinone-4) if You're Seeking Short-Term, High Dose Benefits

Expert
Expert

MK-4 is particularly beneficial for lowering LDL (bad cholesterol), which helps reduce plaque buildup in the arteries and lowers the risk of cardiovascular diseases.

Pick MK-4 (Menaquinone-4) if You're Seeking Short-Term, High Dose Benefits
Source:amazon.com
MK-4 is known for its rapid absorption and shorter half-life in the body compared to MK-7. This makes it ideal for those who need a faster response to support immediate bone health or other short-term therapeutic purposes. 

MK-4 can decrease atherogenesis by reducing low-density lipoproteins or LDL (bad cholesterol), which decreases the risk of plaque buildup in the arteries. This helps prevent the development of cardiovascular disease by promoting better lipid regulation and artery health.


MK-4 is particularly suitable for those who already take frequent doses of other supplements or medications and prefer flexibility in adjusting the dosage of K2 throughout the day. Since MK-4 clears the body more quickly, some may prefer to take it multiple times a day for a more controlled, consistent intake. 


Additionally, research has shown that MK-4 plays a role in bone health and has been used in higher doses of 45 mg to treat osteoporosis, which may benefit individuals under medical supervision needing specific bone support.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
A study involving ten volunteers found that administering MK-4 at the recommended dietary intake (RDI) level did not affect blood levels of this form of vitamin K. While both MK-4 and MK-7 support bone health and insulin action, they require different dosages — 90 mg of MK-4 compared to 200 mcg of MK-7. Although their mechanisms of action may differ, MK-7 is an effective precursor to MK-4, highlighting their interrelated benefits.
3

Look for Products with MCT (Medium-Chain Triglyceride) Oil to Enhance Absorption

Expert
Expert
MCT oil's small particle size aids the absorption of fat-soluble vitamins by allowing them to be absorbed quickly without going through the fat-digestion process.
Look for Products with MCT (Medium-Chain Triglyceride) Oil to Enhance Absorption
Source:amazon.com
Both vitamins D3 and K2 are fat-soluble, meaning they require fat to be adequately absorbed by the body. MCT oil, derived from sources like coconut oil, provides a high-quality fat that can improve the bioavailability of these vitamins, ensuring they are absorbed more efficiently. This is particularly useful for people who may not consume enough healthy fats in their regular diet.

People with digestive sensitivities or conditions impairing fat absorption, such as celiac disease or gallbladder issues, can also benefit from MCT oil supplements. The liver easily digests and directly absorbs MCTs, making them ideal carriers for vitamins D3 and K2.

4

Consider Formulations with Magnesium to Support Cardiovascular, Heart, and Bone Health

Expert
Expert
Magnesium collaborates with vitamins D and K to enhance bone health, muscle function, cardiovascular health, immune response, and sleep quality.
Consider Formulations with Magnesium to Support Cardiovascular, Heart, and Bone Health
Source:amazon.com

Magnesium supports bone health and regulates heart rhythm, blood pressure, and overall cardiovascular function. When combined with D3 and K2, magnesium enhances the effectiveness of these vitamins by ensuring proper calcium metabolism. 


For Cardiovascular Health: Magnesium helps prevent calcium from building up in the arteries, a risk factor for heart disease. This combination is particularly beneficial for those focused on maintaining heart health and preventing arterial calcification.


For Bone Health: Magnesium is essential for activating vitamin D3 and improving bone calcium absorption. Vitamin D3 may not function effectively without adequate magnesium, and calcium may deposit in soft tissues rather than being directed to the bones. Adding magnesium to the formula is helpful for older adults or those at risk of osteoporosis, as it ensures calcium is utilized correctly and contributes to bone health rather than causing harm to arteries or tissues.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
Note that the combination of magnesium with D3 and K2 may cause high magnesium levels, and if you have kidney disease, you should talk to a physician before taking it.
5

Choose the Form of Supplement That Suits Your Condition

Select a supplement form that aligns with your health needs, as different formulations can offer varied absorption rates and benefits.

Opt for an Oil-Based Capsule or Softgel for Better Absorption

Expert
Expert

Oil-based capsules improve the bioavailability of fat-soluble vitamins such as D and K by enhancing their digestion and absorption through the lymphatic or hepatic systems. 

Opt for an Oil-Based Capsule or Softgel for Better Absorption

Since both D3 and K2 are fat-soluble, they must be taken with fat for optimal absorption. Oil-based softgels provide this essential fat within the capsule itself, ensuring that the vitamins are absorbed efficiently, even if the supplement is taken on an empty stomach or with a low-fat meal. This form is ideal for individuals with poor fat intake or those seeking a more reliable, convenient absorption method.


Softgels are often smaller and smoother compared to tablets, making them easier to take, especially for older adults or those who struggle with swallowing pills. 


Softgels provide a pre-measured dose of both vitamins, offering consistency and accuracy in supplementation, which is beneficial for people managing specific health concerns like bone density or cardiovascular health.

Go for a Liquid Form if You Prefer Flexible Dosing or Have Difficulty Swallowing Pills

Expert
Expert
Liquid vitamins are absorbed quickly and are great for those with swallowing or esophageal issues.
Go for a Liquid Form if You Prefer Flexible Dosing or Have Difficulty Swallowing Pills

Liquid supplements allow for easy dosage adjustment to tailor your intake to your specific healthcare needs. This is especially useful for children, older adults, or those needing to increase or decrease their dosage gradually.


Liquids are generally absorbed more rapidly by the body than capsules or tablets, allowing for quicker utilization of the vitamins. This makes liquid vitamin D3 and K2 ideal for individuals who need immediate health support, such as those with severe vitamin deficiencies or people managing acute health conditions related to bone density or cardiovascular health. 


Drops or liquid supplements are often free of unnecessary fillers, providing a purer option for health-conscious consumers. Their liquid form also makes them excellent for individuals with swallowing difficulties who prefer to ingest supplements mixed in food, drinks, or smoothies.

Kathy Shattler, MS, RDN
Registered Dietitian Nutritionist
Kathy Shattler, MS, RDN
Other health enthusiasts may prefer to make their own blends of nutrients and mix them together in a shake. Gradual dose changes are easy to make, as simple as changing the amount in the measuring syringe or dropper.
6

Check for Products That Have Been Third-Party Tested for Purity, Potency, and Safety

Expert
Expert
All supplements should be independently third-party tested for ingredient accuracy and contamination-free status from heavy metals, bacteria, mold, and pesticides.
Check for Products That Have Been Third-Party Tested for Purity, Potency, and Safety
Vitamin D3 and K2 supplements should undergo independent third-party testing to ensure ingredient accuracy and safety. This testing verifies that the supplement contains the exact ingredients and dosages claimed on the label. Third-party testing also checks for contaminants such as heavy metals, bacteria, mold, and pesticides, which can pose significant health risks.

Consumers should actively look for a Certificate of Analysis (COA) for each product, demonstrating that it has been rigorously tested for quality and purity. 


A certification seal from reputable organizations such as NSF, USP, GMP, or ConsumerLab.com indicates that the product has met specific standards for safety and efficacy. These certifications serve as a reliable benchmark for consumers, helping them select high-quality supplements that are both effective and safe for consumption.

Was the Buying Guide helpful?

10 Best Vitamin D3 and K2 Supplements Ranking

Here are the top 10 best-selling vitamin D3 and K2 supplements available on Amazon and iHerb. We independently ranked each supplement according to consumer popularity and our expert-backed buying guide.
Popularity
Filter
Products
Image
Click to purchase
Key features
Details
D3 Dosage
K2 Dosage
K2 Type
MCT Oil
Magnesium
Form
Third-Party Tested
Organic
1

Sports Research

Vitamin D3 + K2 with Coconut MCT Oil

Sports Research Vitamin D3 + K2 with Coconut MCT Oil 1

Plant-Based Power for Bone and Heart Health

5000IU

100mcg

MK-7

Softgel

2

Dr. Berg

D3 & K2 Vitamin (10,000 IU)

Dr. Berg D3 & K2 Vitamin (10,000 IU) 1

Advanced Formula for Superior Absorption

10000IU

100mcg

MK-7

Veg capsule

3

Micro Ingredients

Micro IngredientsVitamin D3 K2 Supplement Softgels

Micro Ingredients Vitamin D3 K2 Supplement Softgels 1

High-Potency D3 and MK-7 K2 with MCT Oil for Maximum Absorption

5000IU

200mcg

MK-7

Softgel

4

Bronson

BronsonVitamin K2 MK-7 Plus Vitamin D3

Bronson Vitamin K2 MK-7 Plus Vitamin D3 1

Advanced Bone and Heart Health Support

5000IU

90mcg

MK-7

Veg capsule

5

Nature Made

Nature MadeVitamin D3 + K2 Softgels

Nature Made Vitamin D3 + K2 Softgels 1

K2 and D3 for Enhanced Calcium Utilization and Artery Health

5000IU

100mcg

MK-7

Softgel

6

Pure Encapsulations

Vitamin D3 & K2

Pure Encapsulations Vitamin D3 & K2 1

Allergen-Free D3 + K2 for Bone, Vascular, and Immune Support

4000IU

100mcg

MK-7

Veg capsule

7

Nusava

Organic Vitamin D3 K2 Drops w MCT Oil Omega 3

Nusava Organic Vitamin D3 K2 Drops w MCT Oil Omega 3 1

Liquid D3 + K2 with Omega-3 for Fast Absorption

5000IU

120mcg

MK-7、MK-4

Liquid

8

NOW Foods

Vitamin D-3 & K-2 Capsules

NOW Foods Vitamin D-3 & K-2 Capsules 1

D3 & K2 in Allergen-Free Capsules

1000IU

45mcg

MK-4

Veg capsule

9

Metagenics

Vitamin D3 10,000 + K

Metagenics Vitamin D3 10,000 + K 1

High-Potency D3 + MK-7 K2 with a Satisfaction Guarantee

10000IU

110mcg

MK-7

Softgel

10

Thorne

Vitamin D + K2 Liquid

Thorne Vitamin D + K2 Liquid 1

Customizable Liquid D3 + K2 Trusted by Health Professionals

1000IU

200mcg

MK-4

Liquid

If you don't see the product you're looking for, you can request that it be listed.
No.1

Sports Research
Vitamin D3 + K2 with Coconut MCT Oil

Vitamin D3 + K2 with Coconut MCT Oil 1
Source:amazon.com
Vitamin D3 + K2 with Coconut MCT Oil 2
Source:amazon.com
Lowest price
$23.95
Mid
Lowest price
$23.95
Mid
D3 Dosage5000IU
K2 Dosage100mcg
K2 Type
MK-7
MCT Oil
Magnesium

Plant-Based Power for Bone and Heart Health

Sports Research Vitamin D3 + K2 combines the potent benefits of 5,000 IU of vegan-certified D3 with 100 mcg of K2 MK-7 to support optimal bone and cardiovascular health. Sourced from lichen, the plant-based D3 in these softgels is ideal for those following a vegan lifestyle, while the K2, derived from chickpea, directs calcium into the bones and teeth, helping to maintain strong bones and reduce arterial plaque formation. This powerful duo is blended with organic coconut oil to enhance absorption, ensuring you get the most out of every dose.


Free from soy and gluten, these easy-to-swallow softgels are designed to fit seamlessly into your daily routine, providing a convenient way to maintain your vitamin D and K levels. With 60 softgels per bottle, Sports Research offers a two-month supply of high-quality, plant-based nutrition, supporting your bone strength and heart health for a well-rounded approach to overall wellness.

FormSoftgel
Third-Party Tested
Organic
Was this Ranking helpful?
No.2

Dr. Berg
D3 & K2 Vitamin (10,000 IU)

Lowest price
$35.99
High Mid
D3 Dosage10000IU
K2 Dosage100mcg
K2 Type
MK-7
MCT Oil
Magnesium

Advanced Formula for Superior Absorption

Dr. Berg’s Vitamin D3 & K2 supplement combines a powerful blend of 10,000 IU of vitamin D3 and 100 mcg of MK7 vitamin K2 to support optimal bone, heart, and immune health. This unique formula includes MCT powder, purified bile salts, zinc, and magnesium, ensuring that your body effectively absorbs and utilizes these essential nutrients. Adding K2 helps guide calcium to the bones and teeth rather than letting it accumulate in the arteries, promoting cardiovascular health.


The addition of magnesium enhances the absorption and metabolism of vitamin D. Without magnesium, vitamin D is stored in the body and cannot be used.


Designed for those who seek maximum absorption, Dr. Berg’s Vitamin D3 K2 supplement is an excellent choice for anyone looking to enhance their vitamin D levels and overall health. Each bottle contains 120 capsules, providing a convenient four-month supply of these vital nutrients. This supplement is perfect for individuals needing a higher dose of vitamin D3 while also benefiting from the added support of vitamin K2, zinc, and magnesium for comprehensive wellness.


While this supplement contains an amount of vitamin D in excess of the tolerable upper limit of 4,000 IU/daily, the addition of vitamin K has a protective effect on D hypervitaminosis, thus preventing the usual side effects associated with excessive D3 consumption.

FormVeg capsule
Third-Party Tested
Organic
No.3

Micro Ingredients
Micro IngredientsVitamin D3 K2 Supplement Softgels

Lowest price
$34.95
High Mid
D3 Dosage5000IU
K2 Dosage200mcg
K2 Type
MK-7
MCT Oil
Magnesium

High-Potency D3 and MK-7 K2 with MCT Oil for Maximum Absorption

Micro Ingredients delivers a high-potency combination of 10,000 IU of Vitamin D3 and 200 mcg of K2 (MK-7) per softgel, designed for optimal calcium absorption and bone health. Adding MCT oil ensures that these fat-soluble vitamins are efficiently absorbed by the body, maximizing their effectiveness in supporting bone density and cardiovascular health.


This formula is free from genetically modified ingredients or GMOs, gluten, soy, dairy, and preservatives. It is designed for those seeking a high-strength option without unwanted additives. Each batch undergoes third-party testing to ensure purity and potency, making it a trusted choice for individuals with higher vitamin D needs.

FormSoftgel
Third-Party Tested
Organic
No.4

Bronson
BronsonVitamin K2 MK-7 Plus Vitamin D3

Lowest price
$14.99
D3 Dosage5000IU
K2 Dosage90mcg
K2 Type
MK-7
MCT Oil
Magnesium

Advanced Bone and Heart Health Support

This supplement provides a powerful combination of 5,000 IU of Vitamin D3 and 90 mcg of Vitamin K2 MK-7 in each capsule. This dynamic duo is designed to support strong bones and cardiovascular health by ensuring calcium is effectively absorbed and directed to where it's needed most — your bones and teeth — rather than accumulating in your arteries. The non-GMO formula makes this supplement a trusted choice for those looking to enhance their vitamin D and K intake.


With 120 easy-to-swallow capsules, Bronson Vitamin K2 with D3 offers a convenient way to maintain optimal levels of these essential vitamins. Including MK-7, the most bioactive form of Vitamin K2, ensures long-lasting effectiveness, making it ideal for daily use. This vitamin D and K complex is excellent for individuals seeking comprehensive bone density, heart health, and overall wellness support.

FormVeg capsule
Third-Party Tested
Organic
No.5

Nature Made
Nature MadeVitamin D3 + K2 Softgels

Lowest price
$13.49
D3 Dosage5000IU
K2 Dosage100mcg
K2 Type
MK-7
MCT Oil
Magnesium

K2 and D3 for Enhanced Calcium Utilization and Artery Health

Nature Made Vitamin D3 + K2 Softgels offer a simple solution for those with higher Vitamin D requirements. They feature 100 mcg of K2 to support calcium metabolism and 5,000 IU of D3 to aid in absorption. This combination is formulated to support both bone health and arterial function, helping to direct calcium to where it’s needed most — your bones.


This product is free from gluten, synthetic dyes, and artificial flavors and is manufactured in the USA using high-quality global ingredients. It’s an ideal choice for those seeking to improve bone density or maintain healthy arteries with a focus on quality and purity.

FormSoftgel
Third-Party Tested
Organic
No.6

Pure Encapsulations
Vitamin D3 & K2

Lowest price
$33.60
High Mid
D3 Dosage4000IU
K2 Dosage100mcg
K2 Type
MK-7
MCT Oil
Magnesium

Allergen-Free D3 + K2 for Bone, Vascular, and Immune Support

Pure Encapsulations Vitamin D3 & K2 offers a clean, allergen-free formula designed to support bone health, vascular function, and immune defense. This supplement has a precise dose of 4,000 IU of D3 and 100 mcg of K2. It aims to improve calcium metabolism, ensuring calcium is effectively utilized in the bones and not deposited in soft tissues like arteries.


The product is made from premium ingredients and is free from wheat, eggs, peanuts, gluten, artificial colors, and GMOs, making it suitable for those with dietary restrictions. Pure Encapsulations also claims to test products in cGMP-certified laboratories to ensure quality.

FormVeg capsule
Third-Party Tested
Organic
No.7

Nusava
Organic Vitamin D3 K2 Drops w MCT Oil Omega 3

Lowest price
$26.99
Mid
D3 Dosage5000IU
K2 Dosage120mcg
K2 Type
MK-7、MK-4
MCT Oil
Magnesium

Liquid D3 + K2 with Omega-3 for Fast Absorption

Nusava offers a convenient liquid D3 + K2 supplement that provides 5,000 IU of Vitamin D3 and 120 mcg of K2 in each serving. The formula also includes omega-3 and MCT oil, both of which help support better absorption of these fat-soluble vitamins.


This USA-made product is suitable for individuals seeking a fast-acting liquid option. It’s particularly beneficial for those who prefer a liquid format for easier dosing or quicker nutrient uptake.

FormLiquid
Third-Party Tested
Organic
No.8

NOW Foods
Vitamin D-3 & K-2 Capsules

Lowest price
$8.59
D3 Dosage1000IU
K2 Dosage45mcg
K2 Type
MK-4
MCT Oil
Magnesium

D3 & K2 in Allergen-Free Capsules

NOW Foods' Vitamin D-3 & K-2 capsules deliver 1,000 IU of Vitamin D3 and 45 mcg of K2 per serving. They support bone health and cardiovascular function by promoting calcium absorption and directing it away from arteries.


This product is certified non-GMO, kosher, and soy-free and manufactured in a facility that adheres to Good Manufacturing Practices (GMP), ensuring high quality and purity. It’s a reliable option for those seeking daily support for bone and heart health.

FormVeg capsule
Third-Party Tested
Organic
No.9

Metagenics
Vitamin D3 10,000 + K

Lowest price
$31.50
D3 Dosage10000IU
K2 Dosage110mcg
K2 Type
MK-7
MCT Oil
Magnesium

High-Potency D3 + MK-7 K2 with a Satisfaction Guarantee

Metagenics Vitamin D3 10,000 + K features a potent 10,000 IU of vitamin D3 and 110 mcg of K2 as MK-7It may be suitable for those needing a higher dose of D3 to support bone health and immune function. The dosage is high, so consult with a doctor to see if this supplement is right for you.



The formula is non-GMO and gluten-free, and the product comes with a 60-day satisfaction guarantee for peace of mind. It's an ideal choice for individuals with high vitamin D needs, particularly those at risk for deficiencies.

FormSoftgel
Third-Party Tested
Organic
No.10

Thorne
Vitamin D + K2 Liquid

Lowest price
$32.00
High Mid
D3 Dosage1000IU
K2 Dosage200mcg
K2 Type
MK-4
MCT Oil
Magnesium

Customizable Liquid D3 + K2 Trusted by Health Professionals

Thorne’s Vitamin D + K2 liquid supplement offers a convenient and flexible way to consume both D3 and K2, supporting bone, muscle, and cardiovascular health. The standard dosage is 1,000 IU of D3 and 200 mcg of K2. The product features a self-dispensing top, ensuring accurate and customizable dosing, making it particularly suitable for those who need precise control over their intake.


Thorne has a reputation for quality and trust among health professionals. They even partner with the Mayo Clinic. Thorne’s liquid D3 + K2 supplement is a reliable choice for anyone seeking to optimize their vitamin intake without capsules or tablets.

FormLiquid
Third-Party Tested
Organic

Potential Side Effects of Vitamin D3 and K2

Expert
Expert
Vitamin K2 is considered very safe with no established upper limit, though it may interact with some medications, such as blood thinners. Vitamin D3 has a tolerable upper limit of 4,000 IU to prevent side effects like nausea and hypercalcemia, but higher doses, such as 50,000 IU per week for eight weeks, are recommended for vitamin D-deficient adults without evidence of adverse effects.

When taken in recommended doses, the combination of vitamin D3 and K2 is generally considered safe. However, taking excessive amounts of D3 can lead to hypercalcemia, where too much calcium accumulates in the blood. This hypervitaminosis can result in symptoms like nausea, vomiting, fatigue, and kidney stones. While K2 helps direct calcium to the bones and away from arteries and has hypervitaminosis protective effects for D3, over-supplementation with D3 can still pose risks, especially if taken in extremely high doses without medical supervision over a prolonged period.


Individuals on blood-thinning medications, like warfarin, need to be cautious with vitamin K2, as it can interfere with the medication's effectiveness by promoting blood clotting. Additional medications that may be affected include anti-seizure drugs, antibiotics, fat-blockers, and others. It's crucial to follow dosage guidelines and consult with a healthcare provider, especially for those with pre-existing conditions or taking any medication.

Top 5 Vitamin D3 and K2 Supplement

No. 1: Sports ResearchVitamin D3 + K2 with Coconut MCT Oil

No. 2: Dr. BergD3 & K2 Vitamin (10,000 IU)

No. 3: Micro IngredientsMicro IngredientsVitamin D3 K2 Supplement Softgels

No. 4: BronsonBronsonVitamin K2 MK-7 Plus Vitamin D3

No. 5: Nature MadeNature MadeVitamin D3 + K2 Softgels

View Full Ranking
The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

Most Viewed
Featured Rankings Similar to Vitamin D3 and K2 Supplements

Greens Powder

10 Best

Search by category

mybest

We connect users with the best tried and true products,
tested by our in-house guides and backed by expert insight.

Copyright mybest All Rights Reserved.