GABA supplements have become increasingly popular in the U.S. for their potential benefits for managing stress, anxiety, and sleep issues. As a naturally occurring neurotransmitter, GABA helps calm the nervous system, making it a valuable aid for those struggling with anxiety or sleepless nights. Many GABA supplements are available in varying dosages, ranging from 100 mg to 750 mg, allowing users to find the right strength for their needs. Products often include natural ingredients like magnesium, 5-HTP, and L-theanine to enhance their calming effects. When choosing a supplement, it's important to consider the form and to be mindful of potential medicine interactions.
In our buying guide, we’ll rank the best GABA supplements available in the U.S., highlighting top brands like NOW, Nature Made, and Olly. Whether you’re looking for a 500 mg dosage to support relaxation or a lower 100 mg option for milder anxiety relief, we've covered options for every preference. From chewable gummies to plant-based capsules, this guide will help you choose the best supplement tailored to your needs.
Quick List - Top GABA Supplement
mybest US' editing team consists of experienced members who have backgrounds in writing, editing, translation, and more. We are dedicated to researching what makes a product or service the best to users in the US in order to create top-quality articles. From skincare, to kitchen appliances, and to DIY supplies, our mission is to find the best ones for you.
Table of Contents
GABA (Gamma-Aminobutyric Acid) supplements are primarily used to promote relaxation, reduce anxiety, and improve sleep quality. As a neurotransmitter, GABA naturally helps calm the nervous system by inhibiting excessive brain activity, which can ease stress and support mental clarity. People who experience chronic stress or anxiety often turn to GABA supplements as a natural way to manage their emotional well-being without the side effects of pharmaceuticals.
In addition to stress relief, GABA is commonly used to support better sleep. By calming the mind and reducing the "racing thoughts" that can disrupt sleep, GABA helps people fall asleep more easily and enjoy deeper, more restful sleep. Athletes and wellness enthusiasts also take GABA to aid recovery, as its calming effects can reduce muscle tension and promote overall relaxation.
The dosage for GABA supplements can range from 50 mg to 3,000 mg per day, depending on individual needs and the specific condition being addressed. It’s generally advised not to exceed 750 mg per single dose to avoid potential side effects such as drowsiness or dizziness. For most users, starting with a lower dose, such as 100–500 mg, is typical, particularly when using GABA for stress relief or mild anxiety. Gradually increasing the dosage allows for safe adjustment based on tolerance and effectiveness.
Individuals seeking enhanced relaxation and better sleep quality should consider GABA supplements with added ingredients like L-theanine or magnesium. The combination of GABA and L-theanine is known for its synergistic effects, providing greater benefits for improved sleep quality and duration than either ingredient alone.
Those looking to manage stress or improve sleep through nervous system regulation might also benefit from GABA supplements that include magnesium. Magnesium plays a crucial role in sleep by interacting with GABA receptors, enhancing GABA’s calming effects, and reducing nervous system excitability. This combination can be particularly effective for individuals experiencing sleep disruptions due to heightened stress or anxiety, as both GABA and magnesium work together to promote relaxation and improve overall sleep quality.
Individuals struggling with mood imbalances, stress, or sleep disturbances should consider GABA supplements combined with 5-HTP. 5-HTP is a precursor to serotonin, a neurotransmitter that plays a key role in mood regulation and feelings of well-being. When paired with GABA, which helps calm the nervous system, this combination can provide a dual benefit by both reducing anxiety and boosting mood. For those seeking a natural approach to managing stress, anxiety, or mild depression, this blend may offer enhanced emotional balance and relaxation.
Additionally, people looking to improve their sleep may benefit from GABA with 5-HTP. Serotonin, derived from 5-HTP, is involved in the production of melatonin, the hormone that regulates sleep-wake cycles. By promoting both serotonin and GABA activity, this combination can help improve sleep quality, making it a good choice for individuals dealing with insomnia or irregular sleep patterns related to mood or stress issues.
Gummies are an ideal choice for individuals who prefer a convenient and pleasant-tasting option for taking GABA supplements. People who struggle with swallowing pills or capsules or simply dislike the process may find gummies easier to incorporate into their daily routine.
Gummies are often formulated with lower doses of GABA, making them suitable for people who prefer a milder effect or are new to GABA supplements. They can be easily taken without water and fit into a pocket or bag, making them convenient for those who want to manage stress or promote relaxation while at work or traveling.
Individuals following a plant-based or vegan lifestyle should opt for plant-based capsules rather than gummies. Gummies often contain gelatin, which is derived from animal products. Plant-based capsules are typically made from materials like cellulose, ensuring that the supplement aligns with vegan or vegetarian dietary preferences.
Additionally, plant-based capsules are often free from added sugars and artificial flavors, which are common in gummies. People looking to avoid extra calories, sugars, or artificial additives should consider capsules as a healthier and more straightforward option. Capsules also allow for more precise dosing compared to gummies, which can be beneficial for individuals needing a specific dose of GABA without the variability that comes with chewable forms.
Individuals who prioritize safety and product transparency should always check for third-party testing when choosing GABA supplements. Third-party testing ensures that the supplement contains exactly what the label claims, without harmful contaminants or additives.
Those with health concerns or sensitivities should particularly look for third-party testing to avoid potential side effects from hidden ingredients or poor-quality sourcing. Certifications like GMP (Good Manufacturing Practice) and NSF (National Sanitation Foundation) demonstrate that the supplement has met high safety and quality standards.
Products | Image | Click to purchase | Key features | Details | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA Dosage | L-Theanine | Magnesium | 5-HTP | Form | Third-Party Certification | Unit Count | Flavor | |||||
1 | OLLY OLLY Vitamins & Supplements.|Goodbye Stress | ![]() | Stay Calm Anytime | 100mg | Gummies | NSF certified | 42 Count | Berry Verbena | ||||
2 | Clean Nutraceuticals CalmAgain All in 1 5 HTP Supplement | ![]() | All-in-One Stress and Mood Support | 750mg | Veg Capsule | 90 Count | Unflavored | |||||
3 | Nature Made Nature Made|Wellblends™ Stress Relief™ Gummies | ![]() | Fast-Acting Stress Support | 100mg | Gummies | 40 Count | Strawberry | |||||
4 | NutraHarmony GABA Supplements | ![]() | Embrace Serenity | 750mg | Veg Capsule | 120 Count | Unflavored | |||||
5 | NOW Foods GABA 750 mg Veg Capsules | ![]() | Potent Nervous System Support | 750mg | Veg Capsule | 100 Count | Unflavored | |||||
6 | THORNE THORNE |PharmaGABA-100 | ![]() | Achieve Calmness and Restful Sleep | 100mg | Veg Capsule | NSF GMP for Dietary Supplements | 60 Count | Natural | ||||
7 | Nutricost GABA | ![]() | High-Potency GABA Support with Nutricost | 750mg | Veg Capsule | NSF GMP for Dietary Supplements | 240 Count | Unflavored | ||||
8 | Double Wood Supplements GABA Supplement | ![]() | Promote Calm and Restful Sleep | 1000mg | Veg Capsule | 300 Count | Unflavored | |||||
9 | Pure Encapsulations GABA | ![]() | Your Ally for Stress Management and Relaxation | 700mg | Veg Capsule | 120 Count | Unflavored | |||||
10 | Source Naturals® Serene Science® GABA | ![]() | Achieve Calm and Relaxation with Serene Science® GABA | 750mg | Gelatin Capsule | 180 Count | Unflavored |
GABA Dosage | 100mg |
---|---|
Form | Gummies |
OLLY Goodbye Stress Gummies offer a simple, delicious way to calm your mind and tackle everyday stress. These strawberry and lemon verbena-flavored gummies combine 100 mg of GABA, a fast-acting ingredient known to support relaxation, with L-Theanine to help you stay centered and focused. Lemon Balm, a soothing botanical, adds another layer of stress support, making these gummies a go-to for relaxation.
Convenience is key with OLLY Goodbye Stress, as these chewable gummies don’t require food or water — simply pop two whenever you need them. With no artificial colors, flavors, or gluten and packed with 42 gummies, they fit seamlessly into a natural wellness routine.
Third-Party Certification | NSF certified |
---|---|
Unit Count | 42 Count |
Flavor | Berry Verbena |
GABA Dosage | 750mg |
---|---|
Form | Veg Capsule |
Clean Nutraceuticals’ CalmAgain All-in-One 5-HTP Supplement offers a powerful combination of GABA, L-Theanine, Ashwagandha, and 5-HTP, designed for comprehensive mood and stress support. Unlike typical supplements that contain lower doses like GABA 100 mg or L-Theanine 100 mg, CalmAgain packs 750 mg of GABA and 200 mg of L-Theanine in each dose, making it a potent solution for both women and men. This advanced blend also includes 500 mg of L-Tryptophan and 200 mg of 5-HTP, working together to promote relaxation, balance mood, and provide overall mental support.
What sets CalmAgain apart is its inclusion of additional ingredients like SAMe, L-Glycine, vitamin D3, B6, magnesium glycinate, and L-Tyrosine, which enhance its effects on mood and stress management. These ingredients combine to create a comprehensive supplement, providing an alternative to multiple individual products like ashwagandha capsules, 5-HTP gummies, or L-Theanine drops.
Third-Party Certification | |
---|---|
Unit Count | 90 Count |
Flavor | Unflavored |
GABA Dosage | 100mg |
---|---|
Form | Gummies |
Nature Made Wellblends™ Stress Relief Gummies offer a convenient and effective solution for managing everyday stress. Each serving contains 200 mg of L-theanine, known for promoting relaxation, and 100 mg of GABA to support a calm mental state. The gluten-free, strawberry-flavored gummies are not only delicious but are free from high fructose corn syrup, artificial flavors, and synthetic dyes, ensuring a clean and natural product.
Backed by Nature Made’s science-based formulations, these gummies are a trusted solution for stress management. As one of the top pharmacist-recommended vitamin and supplement brands, Nature Made delivers high-quality ingredients you can trust. Whether you’re dealing with work-related anxiety or need to unwind after a busy day, this blend provides fast-acting, on-the-go support to help you stay calm and collected.
Third-Party Certification | |
---|---|
Unit Count | 40 Count |
Flavor | Strawberry |
GABA Dosage | 750mg |
---|---|
Form | Veg Capsule |
Discover tranquility with NUTRAHARMONY’s GABA Supplements, featuring a potent 750 mg formula designed to soothe both mind and body. Each capsule combines GABA with 150 mg of L-theanine and magnesium, promoting relaxation, mental clarity, and emotional well-being. This calm blend not only eases tension but also nurtures your nervous system with essential vitamins B6 and B12, supporting a healthy mood and overall vitality. Perfect for those navigating life's demands, these capsules provide a harmonious journey to wellness with each dose.
Proudly manufactured in the USA, NUTRAHARMONY GABA Supplements undergo strict quality control measures, ensuring safety, purity, and efficacy through third-party testing and GMP certification. Each capsule is crafted with the most potent forms of its components to maximize effectiveness. Experience restful sleep and improved cognitive function as this tranquil blend naturally calms your mind and body, helping you maintain emotional balance and embrace a more peaceful life.
Third-Party Certification | |
---|---|
Unit Count | 120 Count |
Flavor | Unflavored |
GABA Dosage | 750mg |
---|---|
Form | Veg Capsule |
NOW Foods GABA 750 mg Veg Capsules offer a powerful dose of gamma-aminobutyric acid, a neurotransmitter naturally produced by the body to promote relaxation and ease nervous tension. This high-potency formula is ideal for individuals seeking strong support for stress and anxiety management. Each capsule is vegan, non-GMO, soy-free, and certified kosher and halal, making it suitable for a wide range of dietary needs.
Manufactured with strict adherence to quality, NOW Foods ensures its products meet the highest standards. These capsules are produced in a GMP-certified facility, guaranteeing stability, potency, and purity. Perfect for those seeking a potent, natural solution for relaxation, these GABA capsules provide easy, effective nervous system support.
Third-Party Certification | |
---|---|
Unit Count | 100 Count |
Flavor | Unflavored |
GABA Dosage | 100mg |
---|---|
Form | Veg Capsule |
THORNE PharmaGABA-100 is a premium GABA supplement designed to promote a calm state of mind and support restful sleep. Each capsule contains 100 mg of naturally sourced gamma-aminobutyric acid, offering a reliable way to help reduce feelings of anxiety and tension. With its high-quality formulation, this supplement is ideal for individuals seeking a natural solution to manage stress and enhance their overall sense of well-being.
This supplement is free from unnecessary fillers and additives, ensuring that you receive only the essential ingredients needed to support relaxation. With 60 capsules in each bottle, THORNE PharmaGABA-100 makes it easy to incorporate this calming supplement into your daily routine, helping you achieve a balanced and tranquil mindset.
Third-Party Certification | NSF GMP for Dietary Supplements |
---|---|
Unit Count | 60 Count |
Flavor | Natural |
GABA Dosage | 750mg |
---|---|
Form | Veg Capsule |
Nutricost GABA offers a powerful 750 mg of GABA per serving, designed to support relaxation and a calm mental state. With 240 capsules in each bottle, it is enough for an 8-month supply when taken as recommended. This supplement is vegetarian-friendly, non-GMO, and gluten-free, making it suitable for a variety of dietary preferences.
Manufactured in a GMP-compliant, FDA-registered facility, Nutricost ensures the highest quality standards for its products. Whether you're seeking to alleviate stress, improve sleep quality, or enhance overall well-being, Nutricost GABA provides a reliable and effective option to help you achieve your health goals.
Third-Party Certification | NSF GMP for Dietary Supplements |
---|---|
Unit Count | 240 Count |
Flavor | Unflavored |
GABA Dosage | 1000mg |
---|---|
Form | Veg Capsule |
Double Wood Supplements GABA offers a powerful support system for those seeking relaxation and improved sleep habits. Each capsule contains 1,000 mg of GABA, an amino acid and inhibitory neurotransmitter that helps promote a sense of calm and tranquility in the brain. With 300 capsules per bottle, you’ll enjoy a generous 150-day supply.
Manufactured in the USA from globally sourced ingredients, these vegan-friendly and gluten-free capsules are designed to fit seamlessly into any wellness routine. Double Wood Supplements prioritizes quality and safety, ensuring their GABA capsules are non-GMO and rigorously tested. Whether you're managing stress during a busy day or preparing for a restful night’s sleep, this supplement provides the support you need to achieve a balanced state of mind.
Third-Party Certification | |
---|---|
Unit Count | 300 Count |
Flavor | Unflavored |
GABA Dosage | 700mg |
---|---|
Form | Veg Capsule |
Pure Encapsulations GABA is expertly formulated to support relaxation and effective stress management. Each capsule contains premium GABA amino acids, which play a crucial role in moderating occasional stress and promoting a sense of calm.
Beyond relaxation, this supplement may also provide immune support during mild stress, helping you maintain overall wellness. With 120 capsules per bottle, it's designed to be a convenient addition to your daily routine for ongoing stress relief. Whether you're navigating a busy day or looking to unwind after a long week, Pure Encapsulations GABA is your trusted companion for fostering a balanced and relaxed state of mind.
Third-Party Certification | |
---|---|
Unit Count | 120 Count |
Flavor | Unflavored |
GABA Dosage | 750mg |
---|---|
Form | Gelatin Capsule |
Serene Science® GABA by Source Naturals is designed to support a calm mind and promote muscle relaxation through its key ingredient, gamma-aminobutyric acid (GABA). With a simple suggested use of just one capsule daily, it’s an effortless addition to your wellness routine, making it easy to enjoy the benefits of GABA without any fuss.
Manufactured in the USA and trusted for over 35 years, Source Naturals prides itself on high-quality supplements that contain no yeast, dairy, eggs, gluten, corn, soy, or wheat. Whether you're looking to unwind after a long day or need support for a calm mindset, Serene Science® GABA offers a reliable solution for enhancing your overall well-being.
Third-Party Certification | |
---|---|
Unit Count | 180 Count |
Flavor | Unflavored |
While GABA supplements are generally taken to reduce anxiety, some users report experiencing increased anxiety or discomfort. This reaction may be due to individual differences in how people process GABA or how the supplement interacts with their brain chemistry. For some, GABA may not cross the blood-brain barrier effectively, leading to inconsistent results. In rare cases, the imbalance caused by taking external GABA can potentially disrupt natural neurotransmitter levels, resulting in heightened anxiety or nervousness.
Additionally, side effects like headaches, dizziness, or digestive issues can contribute to feelings of unease or anxiety in some individuals. It's important to note that such reactions are uncommon, but they highlight the need for caution when starting GABA supplements. Consulting a healthcare provider before use, especially for those with existing mental health conditions, can help minimize any risks.
GABA supplements can interact with various medications, particularly those that affect the central nervous system. Drugs like benzodiazepines, which are prescribed for anxiety and insomnia (e.g., Xanax, Valium), already work by enhancing GABA activity in the brain. Taking GABA supplements alongside these medications can potentially increase the sedative effects, leading to excessive drowsiness, impaired motor function, or even respiratory issues in extreme cases. Similarly, other central nervous system depressants, such as barbiturates or alcohol, may amplify the effects of GABA, raising the risk of adverse side effects.
Additionally, GABA may interact with anticonvulsants used to manage epilepsy, as some of these drugs also influence GABA levels in the brain. Combining GABA supplements with these medications could alter their effectiveness or increase side effects like dizziness or fatigue. It’s essential to consult with a healthcare provider before starting GABA supplements if you are taking any prescription medications, especially those affecting the nervous system, to avoid unwanted interactions.
Taking GABA supplements with gabapentin is generally not recommended without medical guidance, as both affect GABA-related pathways in the nervous system. Gabapentin, although not a direct GABA agonist, is often used to treat nerve pain, seizures, or anxiety by modulating GABA activity. Adding GABA supplements to gabapentin may increase the risk of side effects like excessive drowsiness, dizziness, or impaired coordination, since both substances can have calming and sedative effects.
It’s important to consult a healthcare provider before combining the two, as they can evaluate potential interactions based on individual health conditions. While GABA supplements are typically seen as safe, the combination with gabapentin might lead to an overstimulation of the GABAergic system, potentially causing unwanted side effects or diminishing the effectiveness of one or both substances.
No. 1: OLLY|OLLY Vitamins & Supplements.|Goodbye Stress
No. 2: Clean Nutraceuticals|CalmAgain All in 1 5 HTP Supplement
No. 3: Nature Made|Nature Made|Wellblends™ Stress Relief™ Gummies
No. 4: NutraHarmony|GABA Supplements
No. 5: NOW Foods|GABA 750 mg Veg Capsules
View Full RankingThe descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.
Health
Beauty
Home goods
Home electronics
PC
Camera
Food and drinks
Kitchen
Fashion
Accessories
Kids and baby
Interior
Hobbies
Outdoor
Home, garden, and tools
Sports and fitness
Pets
Media
Games
Apps
Automotive
Gifts
Mobile devices